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Anti-Menin
Anti-Menin

Artikelnummer: A300-105A

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
Schlagworte: Anti-SCG2, Anti-MEN1, Anti-Menin
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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MI-2 (hydrochloride)
MI-2 (hydrochloride)

Artikelnummer: Cay11620-1

Menin, a product of the multiple endocrine neoplasia gene, is an essential component of histone methyltransferase complexes involving the mixed lineage leukemia (MLL) gene product. Also, the leukemogenic activity of MLL fusion proteins depends on their direct interaction with menin. MI-2 potently binds menin, blocks...
Schlagworte: 4-(4-(5,5-dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-propylthieno[2,3-d]pyrimidine, dihydrochloride
Anwendung: Menin binding
MW: 448.5 D
ab 50,00 €
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MI-nc (hydrochloride)
MI-nc (hydrochloride)

Artikelnummer: Cay11621-1

Menin, a product of the multiple endocrine neoplasia gene, is an essential component of histone methyltransferase complexes involving the mixed lineage leukemia (MLL) gene product. Also, the leukemogenic activity of MLL fusion proteins depends on their direct interaction with menin. MI-nc is a weak inhibitor of the...
Schlagworte: 6-ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]-thieno[2,3-d]pyrimidine, dihydrochloride
Anwendung: Menin-MLL inhibitor, Negative control
CAS 1934302-23-4
MW: 405.4 D
ab 84,00 €
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Anti-Menin
Anti-Menin

Artikelnummer: A300-115A

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
Schlagworte: Anti-SCG2, Anti-MEN1, Anti-Menin
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-Menin (IHC)
Anti-Menin (IHC)

Artikelnummer: IHC-00572

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
Schlagworte: Anti-SCG2, Anti-MEN1, Anti-Menin
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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MI-2
MI-2

Artikelnummer: Cay29218-5

MI-2 is an inhibitor of the protein-protein interaction between menin and mixed lineage leukemia (MLL) fusion proteins (IC50 = 446 nM). It binds to menin (Kd = 158 nM) and inhibits the menin interaction with the MLL fusion protein MLL-AF9 in HEK293 cells without affecting protein levels of menin or MLL-AF9. MI-2...
Schlagworte: 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propyl-thieno[2,3-d]pyrimidine
Anwendung: Menin-MLL fusion protein interaction inhibitor
CAS 1271738-62-5
MW: 375.6 D
ab 130,00 €
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Anti-Menin
Anti-Menin

Artikelnummer: ARG10827.50

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
Schlagworte: Anti-SCG2, Anti-MEN1, Anti-Menin
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
528,00 €
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Anti-Menin
Anti-Menin

Artikelnummer: A300-106A

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
Schlagworte: Anti-SCG2, Anti-MEN1, Anti-Menin
Anwendung: WB, IP
Wirt: Goat
Spezies-Reaktivität: human
ab 164,00 €
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Human Secretogranin 2 / Chromogranin C ELISA Kit
Human Secretogranin 2 / Chromogranin C ELISA Kit

Artikelnummer: G-HUFI02838.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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Anti-Menin
Anti-Menin

Artikelnummer: NSJ-R31676

0.5mg/ml if reconstituted with 0.2ml sterile DI water. The MEN1 gene encodes Menin, a nuclear scaffold protein that regulates gene transcription by coordinating chromatin remodeling. It is mapped to 11q13.1. MEN1 is considered to act as a tumor suppressor gene. It has been found that that MEN1 inactivation by...
Schlagworte: Anti-SCG2, Anti-MEN1, Anti-Menin, Menin Antibody
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
755,00 €
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Anti-Menin / MEN1, clone ACBA-13
Anti-Menin / MEN1, clone ACBA-13

Artikelnummer: NSJ-RQ4687

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation....
Schlagworte: Anti-SCG2, Anti-MEN1, Anti-Menin, Menin Antibody / MEN1
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
755,00 €
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MI-3
MI-3

Artikelnummer: Cay27214-1

MI-3 is an inhibitor of the interaction between menin and mixed lineage leukemia (MLL) fusion proteins (IC50 = 648 nM). MI-3 binds to menin (Kd = 201 nM) and inhibits the menin interaction with the MLL fusion protein MLL-AF9 in HEK293 cells without affecting protein levels of menin or MLL-AF9. It inhibits growth of...
Schlagworte: 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(1-methylethyl)-thieno[2,3-d]pyrimidine
Anwendung: MLL / menin interaction inhibitor
CAS 1271738-59-0
MW: 375.6 D
ab 50,00 €
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