Liafensine

Description: Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and central nervous system disorders. Target: Norepinephrine, 5-HT Receptor, Dopamine Receptor. Smiles: CN1C[C@H](C=2C(=CC(=CC2)C3=CC=C(N)N=N3)C1)C4=CC5=C(C=C4)C=CC=C5. References: Risinger R, et al. Evaluation of safety and tolerability, pharmacokinetics, and pharmacodynamics of BMS-820836 in healthy subjects: a placebo-controlled, ascending single-dose study. Psychopharmacology (Berl). 2014 Jun,231(11):2299-310.