LGD 6972 (ammonium salt)

A GCGR antagonist, reduces glucagon-induced hyperglycemia in wild-type mice, reduces blood glucose levels in mouse models of diabetes. Formulation: A solid. InChI: InChI=1S/C43H46N2O5S.H3N/c1-28-25-29(2)40(30(3)26-28)35-17-21-38(22-18-35)45-42(47)39(27-31-7-9-36(10-8-31)41(46)44-23-24-51(48,49)50)34-13-11-32(12-14-34)33-15-19-37(20-16-33)43(4,5)6,/h7-22,25-26,39H,23-24,27H2,1-6H3,(H,44,46)(H,45,47)(H,48,49,50),1H3/t39-,/m1./s1. InChIKey: VZJMFAKZCPXIGY-DRRLCDGFSA-N. SMILES: CC1=C(C2=CC=C(C=C2)NC([C@@H](C3=CC=C(C4=CC=C(C=C4)C(C)(C)C)C=C3)CC5=CC=C(C=C5)C(NCCS(=O)([O-])=O)=O)=O)C(C)=CC(C)=C1.[NH4+]