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Zu "K04583" wurden 26 Artikel gefunden!
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Artikelnummer: Cay29668-1
Adomeglivant is an allosteric antagonist of the glucagon receptor. It inhibits glucagon-induced increases in cAMP levels in HEK293 cells expressing the rat glucagon or GLP-1 receptors (IC50s = 1.8 and 1.2 µM, respectively) but has no effect on cAMP levels when used alone. Adomeglivant also inhibits increases in cAMP...
Schlagworte: | LY2409021,... |
Anwendung: | Allosteric glucagon receptor antagonist |
CAS | 1488363-78-5 |
MW: | 555.6 D |
ab 43,00 €
Artikelnummer: AG-CN2-0001-M001
Non-peptidic anti-diabetic agent, Receptor-selective glucagon antagonist, Free radical species (.OH, R.) and singlet oxygen (1O2) scavenger, Mycotoxin, Cytotoxic, Antioxidant. Isolated from fungus Talaromyces sp.
Schlagworte: | Rhodophyscin, Endothianin |
Anwendung: | Antioxidant, Glucagon antagonist |
CAS | 602-06-2 |
MW: | 538,5 D |
176,00 €
Artikelnummer: Cay24459-1
[Des-His1,Glu9]-Glucagon (1-29) amide is a peptide glucagon receptor antagonist (pA2 = 7.25 for glucagon binding to isolated rat liver membranes). It binds to glucagon receptors in a magnesium- and GTP-independent manner to stimulate breakdown of inositol phospholipids by phospholipase C, but has no effect on...
Schlagworte: | 9-L-glutamic acid-29-L-threoninamide-2-29-glucagon (swine) |
Anwendung: | Peptide glucagon receptor antagonist |
MW: | 3358.7 D |
472,00 €
Artikelnummer: Cay22164-1
Glucagon receptor antagonist 4 is an antagonist of the glucagon receptor (GCGR, Ki = 14 nM for the human recombinant receptor). It is greater than 230-fold selective for GCGR over the glucagon-like peptide 1 (GLP-1) receptor, as well as a panel of 69 receptors, ion channels, uptake sites, and enzymes at 10 µM....
Schlagworte: | GCGR Antagonist IV, N-[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]-beta-alanine |
Anwendung: | GCGR antagonist |
CAS | 1393124-08-7 |
MW: | 503.5 D |
ab 43,00 €
Artikelnummer: E-AB-13269.120
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM). Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose...
Schlagworte: | Anti-GL-R, Anti-GCGR, Anti-Glucagon receptor, GCGR Polyclonal Antibody |
Anwendung: | WB, IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Artikelnummer: Cay21188-1
Glucagon receptor antagonist inactive control is an analog of glucagon receptor antagonist I (Cay-21223). It inhibits glucagon binding to the glucagon receptor (GCGR) by only 20% in CHO cells expressing human GCGR when used at a concentration of 10 µM. Glucagon receptor antagonist inactive control has no effect on...
Schlagworte: | GCGR Inactive Control, 4-bromo-N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-benzamide |
CAS | 362482-00-6 |
MW: | 431.4 D |
ab 240,00 €
Artikelnummer: Cay21223-1
Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR, IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal...
Schlagworte: | GCGR Antagonist I, N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl-butanamide |
Anwendung: | GCGR antagonist |
CAS | 438618-32-7 |
MW: | 346.5 D |
ab 100,00 €
Artikelnummer: Cay29727-1
GRA Ex-25 is a glucagon receptor (GCGR) antagonist (IC50s = 55 and 56 nM for the human and rat receptors, respectively). It inhibits adenylate cyclase activity induced by glucagon (Cay-24204) with a Ki value of 254 nM. GRA Ex-25 (3 mg/kg, i.v.) reduces glucagon-induced increases in blood glucose levels in...
Schlagworte: | N-[4-[[[trans-4-(1,1-dimethylethyl)cyclohexyl][[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]methyl]benzoyl]-beta-alanine |
Anwendung: | Glucagon receptor (GCGR) antagonist |
CAS | 307983-31-9 |
MW: | 563.6 D |
ab 43,00 €
Artikelnummer: G-CAB10617.100
Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting....
Schlagworte: | Anti-GL-R, Anti-GCGR, Anti-Glucagon receptor, GCGR Rabbit pAb |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 352,00 €
Artikelnummer: E-AB-90226.120
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM). Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose...
Schlagworte: | GL-R, GCGR, Glucagon receptor, GCGR Polyclonal Antibody |
Anwendung: | WB, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Artikelnummer: ELK-ES2433.100
glucagon receptor(GCGR) Homo sapiens The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010], Protein function: G-protein coupled receptor for...
Schlagworte: | Anti-GL-R, Anti-GCGR, Anti-Glucagon receptor, Glucagon Receptor rabbit pAb |
Anwendung: | WB, IF, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Artikelnummer: G-HDBS0124.100
Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting....
Schlagworte: | Anti-GCGR, Anti-GL-R, Anti-Glucagon receptor |
Anwendung: | FC |
Wirt: | Human |
Spezies-Reaktivität: | human |
399,00 €