Leucettine L41

Description: Leucettine L41 is an effective dual cdc2-like kinase and DYRKs inhibitor. Target: Others. Smiles: C(\C=1C=C2C(=CC1)OCO2)=C/3\NC(NC4=CC=CC=C4)=NC3=O. References: Naert G, Ferré V, Meunier J, Keller E, Malmström S, Givalois L, Carreaux F, Bazureau JP, Maurice T. Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Abeta25-35 peptide administration in mice. Eur Neuropsychopharmacol. 2015 Nov,25(11):2170-82. doi: 10.1016/j.euroneuro.2015.03.018. Epub 2015 Apr 10. PubMed PMID: 26381812.