Lavendustin B

Lavendustin B is a competitive inhibitor of glucose transporter 1 (Glut1, Ki = 15 µM). It is also an inhibitor of the interaction between HIV-1 integrase and LEDGF/p75 (IC50 = 94.07 µM). Lavendustin B is a weak inhibitor of tyrosine kinases (IC50 = 0.49 µg/ml) and has been used as a negative control for the protein tyrosine kinase inhibitor lavendustin A (Cay-10010268).Formal Name: 5-[bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acid. CAS Number: 125697-91-8. Molecular Formula: C21H19NO5. Formula Weight: 365.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/mL, DMSO: 10 mg/mL, Ethanol: 10 mg/mL. lambdamax: 274 nm. SMILES: OC1=CC=CC=C1CN(C2=CC(C(O)=O)=C(O)C=C2)CC3=CC=CC=C3O. InChi Code: InChI=1S/C21H19NO5/c23-18-7-3-1-5-14(18)12-22(13-15-6-2-4-8-19(15)24)16-9-10-20(25)17(11-16)21(26)27/h1-11,23-25H,12-13H2,(H,26,27). InChi Key: RTYOLBQXFXYMKY-UHFFFAOYSA-N.