Ketanserin tartrate

Description: Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and alpha1-adrenergic receptor antagonist with antihypertensive activity, inhibits serotonin-induced vasoconstriction and platelet activation, and can be used in the study of systemic sclerosis. Target: Adrenergic Receptor, 5-HT Receptor, Serotonin Transporter. Smiles: O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1. References: Tang Q, et al. The 5-HT2 antagonist Ketanserin is an open channel blocker of human cardiac ether-à-go-go-related gene (hERG) potassium channels. Br J Pharmacol. 2008 Oct,155(3):365-73.