JT010

JT010 is a transient receptor potential ankyrin 1 (TRPA1) agonist (EC50 = 0.65 nM in a calcium influx assay). It is selective for TRPA1 over TRP vanilloid 1 (TRPV1), TRPV3, TRPV4, TRP canonical channel 5 (TRPC5), TRP melastatin 2 (TRPM2), and TRPM8 channels at 1 µM.Formal Name: 2-chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)-acetamide. CAS Number: 917562-33-5. Molecular Formula: C16H19ClN2O3S. Formula Weight: 354.9. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mM, Ethanol: 50 mM. SMILES: ClCC(N(C1=NC(C2=CC=C(OC)C=C2)=CS1)CCCOC)=O. InChi Code: InChI=1S/C16H19ClN2O3S/c1-21-9-3-8-19(15(20)10-17)16-18-14(11-23-16)12-4-6-13(22-2)7-5-12/h4-7,11H,3,8-10H2,1-2H3. InChi Key: KZMAWJRXKGLWGS-UHFFFAOYSA-N.