Fosmidomycin (sodium salt)

Fosmidomycin is an antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces that inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Fosmidomycin is active against both Gram-negative and Gram-positive bacteria and the human malarial parasite P. falciparum (IC50 = 290-370 nM).Formal Name: P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt. CAS Number: 66508-37-0. Synonyms: Antibiotic FR31564, FR31564. Molecular Formula: C4H9NO5P . Na. Formula Weight: 205.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 5 mg/ml. SMILES: ON(C([H])=O)CCCP([O-])(O)=O.[Na+]. InChi Code: InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10,/h4,7H,1-3H2,(H2,8,9,10),/q,+1/p-1. InChi Key: ZZPUYRHMTGOTEU-UHFFFAOYSA-M.