FLT3-IN-17

A dual inhibitor of FLT3D835Y and FAK, inhibits growth of HCT116, MDA-MB-231, and A375 cells (GI50s = 0.25, 0.46, and 0.49 µM, respectively). SMILES: CS(NC1=CC=CC(C2=CSC3=C2N=C(N=C3)NC(C=C4)=CC=C4N5CCNCC5)=C1)(=O)=O. InChi Code: InChI=1S/C23H24N6O2S2/c1-33(30,31)28-18-4-2-3-16(13-18)20-15-32-21-14-25-23(27-22(20)21)26-17-5-7-19(8-6-17)29-11-9-24-10-12-29/h2-8,13-15,24,28H,9-12H2,1H3,(H,25,26,27). InChi Key: MGKRFMQUFDKUBA-UHFFFAOYSA-N