Fasudil, Monohydrochloride Salt

The monohydrochloride salt is the form used to prepare formulations of this drug for clinical use. Note that the solubility properties of the mono- and di-HCl salts are different. Kinase inhibitor, has antivasospastic properties. Solubility: Very soluble in water, up to about 175mg/ml , soluble in DMSO up to about 10mg/ml, not soluble in ethanol, pH of a 2% sloution is about 5.5-6, addition of an aqueous solution of this monohydrochloride salt into a buffer solution may significantly alter its solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.