FAK Inhibitor 14

FAK Inhibitor 14
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay14485-10 10 mg -

6 - 10 Werktage*

67,00 €
Cay14485-25 25 mg -

6 - 10 Werktage*

158,00 €
Cay14485-50 50 mg -

6 - 10 Werktage*

296,00 €
Cay14485-100 100 mg -

6 - 10 Werktage*

552,00 €
 
Focal adhesion kinases (FAK) are non-receptor tyrosine kinases that play roles in regulating... mehr
Produktinformationen "FAK Inhibitor 14"
Focal adhesion kinases (FAK) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. FAK inhibitor 14 is a direct inhibitor of FAK1 autophosphorylation, blocking phosphorylation of Y397 with an IC50 value of about 1 µM. There is no known significant effect on the activity of a range of other kinases. FAK inhibitor 14 promotes cell detachment and inhibits cell adhesion of cells in culture. Moreover, it blocks tumor growth in vivo. FAK inhibitor 14 has also been used to demonstrate a role for FAK in the regulation of aortic stiffness.Formal Name: 1,2,4,5-benzenetetramine, tetrahydrochloride. CAS Number: 4506-66-5. Synonyms: Focal Adhesion Kinase Inhibitor 14, NSC 667249, NSC 677249, Y15. Molecular Formula: C6H10N4 . 4HCl. Formula Weight: 284.0. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 20 mg/ml, Water: 20 mg/ml. SMILES: NC1=CC(N)=C(N)C=C1N.Cl.Cl.Cl.Cl. InChi Code: InChI=1S/C6H10N4.4ClH/c7-3-1-4(8)6(10)2-5(3)9,,,,/h1-2H,7-10H2,4*1H. InChi Key: BZDGCIJWPWHAOF-UHFFFAOYSA-N.
Schlagworte: Focal Adhesion Kinase Inhibitor 14, NSC 667249, NSC 677249, Y15, 1,2,4,5-benzenetetramine, tetrahydrochloride
Hersteller: Cayman Chemical
Hersteller-Nr: 14485

Eigenschaften

Anwendung: FAK1 autophosphorylation inhibitor
MW: 284 D
Formel: C6H10N4 . 4HCl
Reinheit: >95%
Format: Crystalline Solid

Datenbank Information

CAS : 4506-66-5| Passende Produkte
KEGG ID : K05725 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H315, H319, H335
P-Sätze: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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