Zu "K05725" wurden 153 Artikel gefunden!
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Anti-FAK / Focal Adhesion Kinase / PTK2
Artikelnummer: NSJ-F54983-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks...
| Schlagworte: | Anti-FAK, Anti-FRNK, Anti-FADK 1, Anti-PPP1R71, Anti-p125FAK, Anti-pp125FAK, EC=2.7.10.2, Anti-Focal adhesion kinase 1,... |
| Anwendung: | IF, FC, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Rat FAK (Focal Adhesion Kinase) ELISA Kit
Artikelnummer: ELK-ELK7143.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat FAK. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat FAK. Next, Avidin...
| Schlagworte: | Fak, FRNK, FADK 1, p125FAK, pp125FAK, EC=2.7.10.2, Focal adhesion kinase 1, Protein-tyrosine kinase 2, Focal adhesion... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human FAK (Focal Adhesion Kinase) ELISA Kit
Artikelnummer: ELK-ELK4811.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FAK. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FAK. Next,...
| Schlagworte: | FAK, FRNK, FADK 1, p125FAK, PPP1R71, pp125FAK, EC=2.7.10.2, Focal adhesion kinase 1, Protein-tyrosine kinase 2, Focal... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Anti-FAK
Artikelnummer: ELK-EA359.50
FAK is a widely expressed cytoplasmic protein tyrosine kinase involved in integrin-mediated signal transduction. It plays an important role in the control of several biological processes, including cell spreading, migration, and survival. Protein function: Non-receptor protein-tyrosine kinase that plays an essential...
| Schlagworte: | Anti-FAK, Anti-FRNK, Anti-FADK 1, Anti-PPP1R71, Anti-p125FAK, Anti-pp125FAK, EC=2.7.10.2, Anti-Focal adhesion kinase 1,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
Anti-FAK (Focal adhesion kinase 1), Rabbit Monoclonal...
Artikelnummer: REV-31-1364-00-R100
FAK1 (Focal Adhesion Kinase 1) is a non-receptor protein tyrosine kinase that is involved in the regulation of cell adhesion, migration, and survival. It is a member of the Src family of kinases. FAK1 is activated by binding to integrins, which are transmembrane proteins that mediate the attachment of cells to the...
| Schlagworte: | Anti-FAK, Anti-FRNK, Anti-FADK 1, Anti-PPP1R71, Anti-p125FAK, Anti-pp125FAK, EC=2.7.10.2, Anti-Focal adhesion kinase 1,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
PF-573228
Artikelnummer: Cay14924-1
Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are overexpressed in many types of cancer. PF-573228 inhibits FAK with IC50 values of 4 and 30-100 nM for a purified...
| Schlagworte: | FAK Inhibitor II, Focal Adhesion Kinase Inhibitor II,... |
| Anwendung: | PTK2 inhibitor |
| CAS | 869288-64-2 |
| MW: | 491.5 D |
ab 43,00 €
PF-431396
Artikelnummer: Cay17665-1
Proline-rich tyrosine kinase 2 (PYK2) and focal adhesion kinase (FAK) are nonreceptor tyrosine kinases that constitute the focal adhesion kinase subfamily. PYK2 is expressed in both bone-forming osteoblasts and bone-resorbing osteoclasts where it has a positive role in osteoclast maturation and bone resorption....
| Schlagworte: | N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methyl-methane... |
| Anwendung: | FAK / PYK2 inhibitor |
| CAS | 717906-29-1 |
| MW: | 506.5 D |
ab 43,00 €
CEP-37440
Artikelnummer: Cay21278-25
CEP-37440 is a dual inhibitor of focal adhesion kinase 1 (FAK1, IC50s = 2.0 and 80 nM for in vitro enzyme and cellular inhibition, respectively) and anaplastic lymphoma kinase (ALK, IC50s = 3.1 and 22 nM for in vitro enzyme and cellular inhibition, respectively). It blocks the proliferation of inflammatory and...
| Schlagworte: | 2-[[5-chloro-2-[[(6S)-6,7,8,9-tetrahydro-6-[4-(2-hydroxyethyl)-1-piperazinyl]-1-methoxy-5H-benzocyclohepten-2-yl]amino]-4-... |
| Anwendung: | FAK1 & ALK inhibitor |
| CAS | 1391712-60-9 |
| MW: | 580.1 D |
ab 48,00 €
GSK2256098
Artikelnummer: Cay22955-1
GSK2256098 is an inhibitor of focal adhesion kinase (FAK). It is selective for FAK, inhibiting only FAK greater than 50% in a panel of 261 kinases. GSK2256098 inhibits FAK autophosphorylation at tyrosine 397 (Y397) in OVCAR8 ovarian, U87MG glioblastoma, and A549 lung cancer cell lines (IC50s = 15, 8.5, and 12 nM,...
| Schlagworte: | 2-[[5-chloro-2-[[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino]-4-pyridinyl]amino]-N-methoxy-benzamide |
| Anwendung: | PTK2 inhibitor |
| CAS | 1224887-10-8 |
| MW: | 414.9 D |
ab 46,00 €
Anti-PTK2
Artikelnummer: G-CAB11195.100
WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:50 - 1:100. Protein function: Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions,...
| Schlagworte: | Anti-FAK, Anti-FRNK, Anti-PTK2, Anti-FADK 1, Anti-PPP1R71, Anti-p125FAK, Anti-pp125FAK, EC=2.7.10.2, Anti-Focal adhesion... |
| Anwendung: | WB, IHC, IF, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Anti-phospho-FAK (Focal adhesion kinase) (Tyr397), clone...
Artikelnummer: 0091-100
| Schlagworte: | Anti-phospho-PTK2 (pY397) |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, dog |
383,00 €
PND1186
Artikelnummer: Cay17668-5
PND1186 is a potent reversible focal adhesion kinase (FAK) inhibitor with an IC50 value of 1.5 nM against the recombinant enzyme and 100 nM in breast carcinoma cells. It promotes 4T1 breast carcinoma and ID8 ovarian carcinoma cell apoptosis when grown in anchorage-independent 3D cultures but had limited efficacy in...
| Schlagworte: | SR 2516, VS-4718, 2-[[2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methyl-benzamide |
| Anwendung: | FAK inhibitor |
| CAS | 1061353-68-1 |
| MW: | 501.5 D |
ab 77,00 €