Zu "K05725" wurden 183 Artikel gefunden!
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GSK215
Artikelnummer: Cay40835-10
GSK215 is a proteolysis-targeting chimera (PROTAC) composed of the focal adhesion kinase (FAK) inhibitor PND1186 (Cay-17668) linked to the von-Hippel Lindau (VHL) E3 ligase ligand VHL-021. It binds to the FAK kinase domain (IC50 = 15.8 nM) and induces FAK degradation in A549 lung cancer cells with a 50% degradation...
| Schlagworte: | (2S,4R)-4-hydroxy-1-((S)-2-(2-(4-(3-methoxy-4-((4-((2-(methylcarbamoyl)phenyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino... |
| Anwendung: | FAK (PTK2) degradation driving PROTAC |
| CAS | 2743427-26-9 |
| MW: | 985.1 D |
ab 154,00 €
Focal adhesion kinase 1 (PTK2), partial, chicken,...
Artikelnummer: CSB-RP144494CH.1
Organism: Gallus gallus (Chicken). Source: E.coli. Expression Region: 376-683aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: LANNEKQGVR SHTVSVSETD DYAEIIDEED TYTMPSTRDY EIQRERIELG RCIGEGQFGD VHQGIYMSPE NPAMAVAIKT CKNCTSDSVR EKFLQEALTM RQFDHPHIVK LIGVITENPV WIIMELCTLG ELRSFLQVRK...
| Schlagworte: | FAK, FRNK, PTK2, FADK 1, p125FAK, pp125FAK, EC=2.7.10.2, p41/p43FRNK, Focal adhesion kinase 1, Protein-tyrosine kinase 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | chicken |
| MW: | 62.3 kD |
ab 354,00 €
Anti-PTK2
Artikelnummer: CSB-PA002465.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-FAK, Anti-FRNK, Anti-FADK 1, Anti-p125FAK, Anti-PPP1R71, Anti-pp125FAK, EC=2.7.10.2, Anti-Focal adhesion kinase 1,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
106,00 €
Anti-PTK2
Artikelnummer: CSB-PA002474.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-FAK, Anti-FRNK, Anti-FADK 1, Anti-p125FAK, Anti-PPP1R71, Anti-pp125FAK, EC=2.7.10.2, Anti-Focal adhesion kinase 1,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
106,00 €
Anti-PTK2
Artikelnummer: CSB-PA002475.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-FAK, Anti-FRNK, Anti-FADK 1, Anti-p125FAK, Anti-PPP1R71, Anti-pp125FAK, EC=2.7.10.2, Anti-Focal adhesion kinase 1,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-Phospho-PTK2 (Tyr576)
Artikelnummer: CSB-PA011467.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-FAK, Anti-phospho-FRNK, Anti-phospho-FADK 1, Anti-phospho-p125FAK, Anti-phospho-PPP1R71,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
330,00 €
Anti-Phospho-PTK2 (Y861)
Artikelnummer: CSB-PA000526.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-FAK, Anti-phospho-FRNK, Anti-phospho-FADK 1, Anti-phospho-p125FAK, Anti-phospho-PPP1R71,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 106,00 €
Anti-Phospho-PTK2 (Y407)
Artikelnummer: CSB-PA000702.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-FAK, Anti-phospho-FRNK, Anti-phospho-FADK 1, Anti-phospho-p125FAK, Anti-phospho-PPP1R71,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 106,00 €
Anti-Phospho-PTK2 (Y397)
Artikelnummer: CSB-PA000710.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-FAK, Anti-phospho-FRNK, Anti-phospho-FADK 1, Anti-phospho-p125FAK, Anti-phospho-PPP1R71,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-Phospho-PTK2 (S843)
Artikelnummer: CSB-PA040072.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-FAK, Anti-phospho-FRNK, Anti-phospho-FADK 1, Anti-phospho-p125FAK, Anti-phospho-PPP1R71,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-Phospho-PTK2 (Y397)
Artikelnummer: CSB-PA040073.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-FAK, Anti-phospho-FRNK, Anti-phospho-FADK 1, Anti-phospho-p125FAK, Anti-phospho-PPP1R71,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-Phospho-PTK2 (Y576)
Artikelnummer: CSB-PA040074.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-FAK, Anti-phospho-FRNK, Anti-phospho-FADK 1, Anti-phospho-p125FAK, Anti-phospho-PPP1R71,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €