Detomidine (hydrochloride)

Detomidine is a selective alpha2-adrenoceptor agonist (Ki = 1.62 nM) that binds to alpha1-adrenoceptors with much weaker potency (Ki = 415 nM). Formulations containing detomidine have been used as veterinary sedatives.Formal Name: 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole, monohydrochloride. CAS Number: 90038-01-0. Synonyms: MPV 253AII. Molecular Formula: C12H14N2 . HCl. Formula Weight: 222.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 213 nm. SMILES: CC1=C(C)C(CC2=CNC=N2)=CC=C1.Cl. InChi Code: InChI=1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12,/h3-5,7-8H,6H2,1-2H3,(H,13,14),1H. InChi Key: OIWRDXKNDCJZSM-UHFFFAOYSA-N.