Demethoxycurcumin

Description: 1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic effect. 5. Demethoxycurcumin is a potential additive natural product in combination with chemotherapeutic agents in drug-resistant cancers. 6. Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells. Target: Autophagy, Antibacterial, Apoptosis, Antioxidant. Smiles: COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2)ccc1O. References: Shieh J M , Chen Y C , Lin Y C , et al. Demethoxycurcumin Inhibits Energy Metabolic and Oncogenic Signaling Pathways through AMPK Activation in Triple-Negative Breast Cancer Cells[J]. Journal of Agricultural and Food Chemistry, 2013, 61(26):6366-6375.