Chlorzoxazone-d3

Chlorzoxazone-d3 is intended for use as an internal standard for the quantification of chlorzoxazone (Cay-18869) by GC- or LC-MS. Chlorzoxazone is a centrally acting muscle relaxant and an activator of small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 µM for KCa2.2 and KCa3.1, respectively). In vivo, chlorzoxazone (10 mg/kg) decreases alcohol, but not water, intake in a dose-dependent manner and reduces the propensity for rapid initial alcohol intake in rats with intermittent, but not continuous, access to alcohol. Formulations containing chlorzoxazone have been used in the treatment of pain and stiffness caused by muscle spasm.Formal Name: 5-chloro-2(3H)-benzoxazolone-4,6,7-d3. CAS Number: 1185173-60-7. Molecular Formula: C7HClD3NO2. Formula Weight: 172.6. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: soluble, DMSO: soluble, Methanol: soluble. SMILES: O=C1OC2=C([2H])C([2H])=C(Cl)C([2H])=C2N1. InChi Code: InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10)/i1D,2D,3D. InChi Key: TZFWDZFKRBELIQ-CBYSEHNBSA-N.