CGP 36216 (hydrochloride)

CGP 36216 is a selective antagonist of GABAB receptors (IC50 = 43 µM). Its action is reversed by the GABAB receptor agonist baclofen. It is active at presynaptic, but not postsynaptic, receptors.Formal Name: p-(3-aminopropyl)-p-ethyl-phosphinic acid, monohydrochloride. CAS Number: 1781834-71-6. Molecular Formula: C5H14NO2P . HCl. Formula Weight: 187.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.25 mg/ml, DMSO: 20 mg/ml, Ethanol: 5 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O=P(CC)(CCCN)O.Cl. InChi Code: InChI=1S/C5H14NO2P.ClH/c1-2-9(7,8)5-3-4-6,/h2-6H2,1H3,(H,7,8),1H. InChi Key: CFQFXUJBWMPODB-UHFFFAOYSA-N.