Cepharanthine

Cepharanthine
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay19648-50 50 mg -

6 - 10 Werktage*

44,00 €
Cay19648-100 100 mg -

6 - 10 Werktage*

75,00 €
Cay19648-500 500 mg -

6 - 10 Werktage*

167,00 €
Cay19648-1 1 g -

6 - 10 Werktage*

275,00 €
 
Cepharanthine is a biscoclaurine alkaloid extracted from S. cepharantha that is cationic and... mehr
Produktinformationen "Cepharanthine"
Cepharanthine is a biscoclaurine alkaloid extracted from S. cepharantha that is cationic and amphipathic and has been reported to decrease the fluidity of biological membranes. It exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models. Cepharanthine can decrease LPS-stimulated expression of TNF-alpha, IL-6, and IL-1beta in macrophages and prevent the activation of NF-kappaB, ERK, JNK, and p38 MAPK. It has also been shown to inhibit cell and tumor growth, inducing G1 phase cell cycle arrest and apoptosis, and decreasing expression of STAT3, Bcl-xL, c-Myc, and cyclin D1 in osteosarcoma models.Formal Name: 2,3,13,14,14aS,15,26,26aR-octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline. CAS Number: 481-49-2. Synonyms: O-Methylcepharanoline, NSC 623442. Molecular Formula: C37H38N2O6. Formula Weight: 606.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml, DMSO: 5 mg/ml, Ethanol: 2 mg/ml. lambdamax: 283 nm. SMILES: CN1CCC(C=C(OCO2)C2=C3OC4=C(OC)C=C(CCN(C)[C@]5([H])CC6=CC=C(OC)C7=C6)C5=C4)=C3[C@]1([H])CC8=CC=C(O7)C=C8. InChi Code: InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1. InChi Key: YVPXVXANRNDGTA-WDYNHAJCSA-N. Origin: Plant/Stephania japonica.
Schlagworte: NSC 623442, O-Methylcepharanoline, 2,3,13,14,14aS,15,26,26aR-octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline
Hersteller: Cayman Chemical
Hersteller-Nr: 19648

Eigenschaften

Anwendung: Biological membrane fluidity reducer, antiparasitic, antimalarial, antiviral, antiinflammatory
MW: 606.7 D
Formel: C37H38N2O6
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

CAS : 481-49-2| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H302
P-Sätze: P264, P270, P330, P301+P310, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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