Cephacetrile

Cephacetrile is a cephalosporin antibiotic. It is active against numerous Gram-positive and Gram-negative bacteria, including clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, and Klebsiella (MICs = 0.64, 0.64, 0.16, 6.25 and 3.12 µg/ml, respectively). Cephacetrile (30 µg/disc) is also active against veterinary isolates of S. aureus from bovine mastitis. Formulations containing cephacetrile have been used in the treatment of bovine mastitis.Formal Name: (6R,7R)-3-[(acetyloxy)methyl]-7-[(2-cyanoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. CAS Number: 10206-21-0. Synonyms: Cefacetrile, 7-Cyanoacetamidocephalosporanic Acid. Molecular Formula: C13H13N3O6S. Formula Weight: 339.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: sparingly, DMSO: slightly soluble, Methanol: slightly soluble. SMILES: O=C(OCC(CS[C@]1([H])[C@@H]2NC(CC#N)=O)=C(C(O)=O)N1C2=O)C. InChi Code: InChI=1S/C13H13N3O6S/c1-6(17)22-4-7-5-23-12-9(15-8(18)2-3-14)11(19)16(12)10(7)13(20)21/h9,12H,2,4-5H2,1H3,(H,15,18)(H,20,21)/t9-,12-/m1/s1. InChi Key: RRYMAQUWDLIUPV-BXKDBHETSA-N.