CB-86

CB-86 is a resorcinol-anandamide hybrid compound that acts as a partial agonist for the central cannabinoid (CB1) receptor and a neutral antagonist for the peripheral cannabinoid (CB2) receptor with Ki values of 5.6 and 7.9 nM, respectively. Its demonstrated potency is similar to that of WIN 55,212-2 (Ki = 21 and 2.1 nM for CB1 and CB2, respectively). CB-86 (1 mg/kg) exhibits antinociceptive effects in mice treated with formalin.Formal Name: N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-hydroxyphenoxy]-octanamide. CAS Number: 1150586-64-3. Molecular Formula: C26H43NO3. Formula Weight: 417.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. lambdamax: 206, 275 nm. SMILES: CC(C1=CC(O)=CC(OCCCCCCCC(NC2CC2)=O)=C1)(C)CCCCCC. InChi Code: InChI=1S/C26H43NO3/c1-4-5-6-11-16-26(2,3)21-18-23(28)20-24(19-21)30-17-12-9-7-8-10-13-25(29)27-22-14-15-22/h18-20,22,28H,4-17H2,1-3H3,(H,27,29). InChi Key: PVAOGZXUOOHSMN-UHFFFAOYSA-N.