CAY10587

CAY10587 is a selective FFAR1 (GPR40) agonist (EC50 = 32 nM) that does not exhibit activity on the related FFARs: FFAR2 (GPR43) or FFAR3 (GPR41). At 100 nM, CAY10587 increases glucose-stimulated insulin secretion in the rat insulin-secreting cell line INS-1E.Formal Name: 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoic acid. CAS Number: 1082058-99-8. Molecular Formula: C18H16O2. Formula Weight: 264.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 15 mg/ml. lambdamax: 286, 295, 305 nm. SMILES: CC1=C(C#CC2=CC=C(CCC(O)=O)C=C2)C=CC=C1. InChi Code: InChI=1S/C18H16O2/c1-14-4-2-3-5-17(14)12-10-15-6-8-16(9-7-15)11-13-18(19)20/h2-9H,11,13H2,1H3,(H,19,20). InChi Key: FODHWOBAQBTTFS-UHFFFAOYSA-N.