Carbamazepine-d10

Carbamazepine-d10 is intended for use as an internal standard for the quantification of carbamazepine by GC- or LC-MS. Carbamazepine is an anticonvulsant. It reduces the occurrence of seizures in mouse models of tonic-clonic, or maximal electroshock-induced, seizures (ED50s = 15.46 and ~13 mg/kg, respectively). Dietary administration of carbamazepine (0.75% w/w) reduces immobility time in the tail suspension test. It also attenuates clonidine-induced aggressive behavior in mice. Formulations containing carbamazepine have been used in the treatment of epilepsy and bipolar disorder.Formal Name: 5H-dibenz[b,f]azepine-1,2,3,4,6,7,8,9,10,11-d10-5-carboxamide. CAS Number: 132183-78-9. Synonyms: Carbazepine-d10, CBZ-d10. Molecular Formula: C15H2D10N2O. Formula Weight: 246.3. Purity: >99% deuterated forms (d1-d10). Formulation: (Request formulation change), A solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 3 mg/ml. SMILES: O=C(N1C2=C([2H])C([2H])=C([2H])C([2H])=C2C([2H])=C([2H])C3=C([2H])C([2H])=C([2H])C([2H])=C31)N. InChi Code: InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)/i1D,2D,3D,4D,5D,6D,7D,8D,9D,10D. InChi Key: FFGPTBGBLSHEPO-LHNTUAQVSA-N.