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Zu "K04833" wurden 44 Artikel gefunden!
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NEU
Artikelnummer: Cay38904-10
Levobupivacaine-d9 is intended for use as an internal standard for the quantification of levobupivacaine (Cay-31596) by GC- or LC-MS. Levobupivacaine is a sodium channel blocker and local anesthetic, as well as the levorotary stereoisomer of bupivacaine (Cay-16618). It inhibits cardiac sodium channel currents (INa)...
Schlagworte: | (S)-(-)-Bupivacaine-d9, 1-butyl-d9-N-(2,6-dimethylphenyl)-(2S)-2-piperidinecarboxamide, monohydrochloride |
Anwendung: | GC-MS, LC-MS internal standard, quantification, sodium channel blocker, local anesthetic |
MW: | 333.9 D |
ab 82,00 €
NEU
Artikelnummer: Cay40428-10
AA43279 is an activator of voltage-gated sodium channel 1.1 (Nav1.1, EC50 = 9.5 µM in a patch-clamp assay using HEK293 cells expressing the human channel). It is selective for Nav1.1 over Nav1.4 and Nav1.7 at 30 µM but also activates Nav1.2, Nav1.5, and Nav1.6 (EC50s = 22.8, 14.4, and 11.6 µM, respectively). AA43279...
Schlagworte: | 3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide |
Anwendung: | Nav1.1 activator |
CAS | 354812-16-1 |
MW: | 248.3 D |
ab 66,00 €
Artikelnummer: Cay35008-10
Eslicarbazepine is a voltage-gated sodium channel (Nav) inhibitor and an active metabolite of the prodrug eslicarbazepine acetate (Cay-23656). It enhances slow activation of voltage-gated sodium channels, reducing channel availability. Eslicarbazepine is protective against seizures induced by maximal electroshock...
Schlagworte: | (S)-Licarbazepine, BIA 2-194, CGP 13751, (10S)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide |
Anwendung: | Eslicarbazepine acetate active metabolite, voltage-gated sodium channel inhibitor |
CAS | 104746-04-5 |
MW: | 254.3 D |
ab 48,00 €
Artikelnummer: Cay23402-1
Mepivacaine (Cay-23402) is an analytical reference standard that is categorized as an anesthetic. This product is intended for research and forensic applications.Formal Name: N-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamide. CAS Number: 96-88-8. Molecular Formula: C15H22N2O. Formula Weight: 246.4. Purity:...
Schlagworte: | N-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamide |
Anwendung: | Analytical reference standard, Anesthetic |
CAS | 96-88-8 |
MW: | 246.4 D |
ab 42,00 €
Artikelnummer: Cay30059-1
Tetracaine (Cay-30059) is an analytical reference standard categorized as an anesthetic. Tetracaine has been found as an adulterant in products marketed as male sexual function enhancers. This product is intended for research and forensic applications.Formal Name: 4-(butylamino)-benzoic acid, 2-(dimethylamino)ethyl...
Schlagworte: | Tetracain, 4-(butylamino)-benzoic acid, 2-(dimethylamino)ethyl ester |
Anwendung: | Analytical reference standard, Local anesthetic, Adulterant |
CAS | 94-24-6 |
MW: | 264.4 D |
ab 39,00 €
Artikelnummer: Cay28884-2.5
Quinidine-d3 is intended for use as an internal standard for the quantification of quinidine (Cay-20356) by GC- or LC-MS. Quinidine is a stereoisomer of the antimalarial agent quinine (Cay-23958) and a class Ia antiarrhythmic agent. Quinidine blocks the voltage-gated sodium (Nav) channel Nav1.5 in a use-dependent...
Schlagworte: | (+)-Quinidine-d3, beta-Quinidine-d3, 6'-(methoxy-d3)-cinchonan-9S-ol |
Anwendung: | GC-MS, LC-MS, internal standard, quantification, sodium channel blocker |
CAS | 1267657-68-0 |
MW: | 327.4 D |
448,00 €
Artikelnummer: Cay17340-10
Oxcarbazepine is a prodrug form of the antiepileptic compound 10,11-dihydro-10-hydroxy carbamazepine (Cay-18467). It inhibits high-frequency repetitive firing of rat spinal cord neurons when used at a concentration of 1 µM. Oxcarbazepine protects against electroshock-induced tonic hindlimb extension (ED50 = 10-20...
Schlagworte: | GP47680, 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide |
Anwendung: | 10-hydroxycarbazepine prodrug, voltage-gated sodium channel blocker |
CAS | 28721-07-5 |
MW: | 252.3 D |
ab 43,00 €
Artikelnummer: Cay24183-100
Zonisamide is a broad-spectrum sulfonamide antiepileptic agent. It selectively blocks the repeated firing of sodium channels (IC50 = 2 µg/ml) at low concentrations in mouse embryo spinal cord neurons, and it blocks spontaneous channel firing at concentrations above 10 µg/ml. In rat cerebral cortex neurons,...
Schlagworte: | CI-912, PD 110843, 1,2-benzisoxazole-3-methanesulfonamide |
Anwendung: | Antiepileptic |
CAS | 68291-97-4 |
MW: | 212.2 D |
ab 77,00 €
Artikelnummer: Cay18467-10
10,11-dihydro-10-hydroxy Carbamazepine is an antiepileptic agent and active metabolite of the prodrug oxcarbazepine (Cay-17340). It is a racemic mixture of (R)- and (S)-10,11-dihydro-10-hydroxy carbamazepine. (S)-10,11-dihydro-10-hydroxy Carbamazepine protects against seizures induced by maximal electroshock (MES)...
Schlagworte: | 10,11-hydroxy-10,11 Dihydrocarbamezer, BIA 2-005, GP 47779, Licarbazepine,... |
Anwendung: | Anticonvulsant, voltage-gated sodium channel SCN1A, SCN2A, SCN3A, SCN4A, SCN5A, SCN8A, SCN9A blocker |
CAS | 29331-92-8 |
MW: | 254.3 D |
ab 68,00 €
Artikelnummer: Cay18870-10
Lennox-Gastaut syndrome (LGS) is a severe pediatric epilepsy syndrome characterized by multiple seizure types. Rufinamide is an anticonvulsant. It inhibits the activation of voltage-gated sodium channel 1.1 (Nav1.1) when used at a concentration of 100 µM. Rufinamide inhibits Nav1.1, but not Nav1.2, Nav1.3, and...
Schlagworte: | CGP 33101, RUF 331, 1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide |
Anwendung: | Antiepileptic |
CAS | 106308-44-5 |
MW: | 238.2 D |
ab 43,00 €
Artikelnummer: Cay23889-100
Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker, in vivo. It induces less tissue damage compared with two other phenytoin prodrugs in rats following subcutaneous and intramuscular administration. Fosphenytoin has anticonvulsant activity in a mouse...
Schlagworte: | ACC-9653, Cl-982, 5,5-diphenyl-3-[(phosphonooxy)methyl]-2,4-imidazolidinedione, disodium salt |
Anwendung: | Voltage-gated sodium channel blocker prodrug |
CAS | 92134-98-0 |
MW: | 406.2 D |
ab 60,00 €
Artikelnummer: Cay33486-1
Carbamazepine-d10 is intended for use as an internal standard for the quantification of carbamazepine by GC- or LC-MS. Carbamazepine is an anticonvulsant. It reduces the occurrence of seizures in mouse models of tonic-clonic, or maximal electroshock-induced, seizures (ED50s = 15.46 and ~13 mg/kg, respectively)....
Schlagworte: | Carbazepine-d10, 5H-dibenz[b,f]azepine-1,2,3,4,6,7,8,9,10,11-d10-5-carboxamide |
Anwendung: | Internal standard, GC-MS, LC-MS, Quantification, Anticonvulsant |
CAS | 132183-78-9 |
MW: | 246.3 D |
ab 147,00 €