Carazolol-d7

Carazolol-d7 is intended for use as an internal standard for the quantification of carazolol (Cay-18628) by GC- or LC-MS. Carazolol is a beta-adrenergic receptor (beta-AR) ligand (Kds = 0.2, 0.03, and 4.47 nM for the human beta1-, beta2-, and beta3-ARs, respectively). It reduces epinephrine-induced increases in mean arterial blood pressure and heart rate in conscious pigs when administered at a dose of 10 µg/kg. Carazolol has been found in wastewater effluent. Formulations containing carazolol have been used to reduce stress in livestock during transport.Formal Name: 1-((9H-carbazol-4-yl)oxy)-3-((propan-2-yl-d7)amino)propan-2-ol. CAS Number: 1173021-02-7. Synonyms: (±)-Carazolol-d7. Molecular Formula: C18H15D7N2O2. Formula Weight: 305.4. Purity: >99% deuterated forms (d1-d7). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly, Methanol: very slightly. SMILES: OC(CNC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])COC1=C(C(C=CC=C2)=C2N3)C3=CC=C1. InChi Code: InChI=1S/C18H22N2O2/c1-12(2)19-10-13(21)11-22-17-9-5-8-16-18(17)14-6-3-4-7-15(14)20-16/h3-9,12-13,19-21H,10-11H2,1-2H3/i1D3,2D3,12D. InChi Key: BQXQGZPYHWWCEB-QLWPOVNFSA-N.