C12-Ceramide

Description: C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activity in the plasma of patients with Niemann-Pick disease. Smiles: CCCCCCCCCC CCC\C=C\[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCC. References: He X, et al. A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann-Pick disease. Anal Biochem. 2003 Mar 1,314(1):116-20.