Zu "K12348" wurden 54 Artikel gefunden!

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SABRAC
SABRAC

Artikelnummer: TGM-T68441-10mg

Description: SABRAC inhibits acid ceramidase in PC3 MC metastatic prostate cancer cells (IC50 = <1 µM), as well as induces accumulation of ceramides in the same cells. Target: Others. Smiles: [C@H]([C@@H](CCCCCCCCCC CCCCC)O)(NC(CBr)=O)CO
Anwendung: Acid ceramidase inhibitor
CAS 886212-98-2
MW: 422.44 D
ab 158,00 €
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SACLAC
SACLAC

Artikelnummer: TGM-T83653-100mg

Description: SACLAC is a cysteine asparaginase activation inhibitor with antitumor activity that decreases AML cell viability, inhibits AML cell proliferation, increases AML cell death, and induces apoptosis of AML cells, and is used in the study of acute myeloid leukemia and cancer. Target: Apoptosis, Caspase....
Anwendung: Acid ceramidase inhibitor
CAS 2248703-42-4
MW: 377.99 D
ab 194,00 €
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SOCLAC
SOCLAC

Artikelnummer: TGM-T84961-10mg

Description: SOCLAC, a derivative of the acid ceramidase inhibitor SABRAC, functions as an irreversible inhibitor of acid ceramidase with an inhibition constant (Ki) of 40.2 nM. Target: Others. Smiles: [C@H]([C@@H](/C=C/CCCCCCCCCC CCC)O)(NC(CCl)=O)CO
Schlagworte: N-chloroacetyl Sphingosine
Anwendung: Acid ceramidase inhibitor
CAS 126586-82-1
MW: 376 D
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SOBRAC
SOBRAC

Artikelnummer: TGM-T84964-10mg

Description: SOBRAC, a derivative of the acid ceramidase inhibitor SABRAC, acts as an irreversible inhibitor of acid ceramidase (Ki= 29.7 nM). Target: Others. Smiles: [C@H]([C@@H](/C=C/CCCCCCCCCC CCC)O)(NC(CBr)=O)CO
Anwendung: Acid ceramidase inhibitor
CAS 362678-28-2
MW: 420.4 D
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ASAH1 Protein, Human, Recombinant (His & SUMO)
ASAH1 Protein, Human, Recombinant (His & SUMO)

Artikelnummer: TGM-TMPH-00880-100ug

Description: ASAH1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 58.7 kDa and the accession number is Q13510.
Schlagworte: N-acylsphingosine amidohydrolase, Acylsphingosine deacylase, Acid CDase, HSD33, AC, ASAH1, ACDase, HSD-33, ASAH, Acid...
MW: 58.7 kD
ab 198,00 €
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ASAH1 Protein, Mouse, Recombinant (GST & His & Myc)
ASAH1 Protein, Mouse, Recombinant (GST & His & Myc)

Artikelnummer: TGM-TMPH-02490-100ug

Description: ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10XHis-GST and C-Myc tag. The predicted molecular weight is 43.8 kDa and the accession number is Q9WV54.
Schlagworte: ASAH, Acid CDase, ASAH1, HSD-33, Acid ceramidase, N-acylsphingosine amidohydrolase, AC, PHP32, HSD33, ACDase,...
MW: 43.8 kD
ab 281,00 €
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LCL521
LCL521

Artikelnummer: TGM-T11835-100mg

Description: LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor. Target: Others, Phospholipase. Smiles: [C@@H]([C@H](NC(CCCCCCCCCC CCC)=O)COC(CN(C)C)=O)(OC(CN(C)C)=O)C1=CC=C(N(=O)=O)C=C1. References: Bai A, et al. Targeting (cellular) lysosomal acid ceramidase...
Anwendung: Acid ceramidase inhibitor
CAS 1226851-11-1
MW: 592.77 D
ab 986,00 €
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ARN14974
ARN14974

Artikelnummer: TGM-T21658-1mg

Description: ARN14974 is a benzoxazolone carboxamide. ARN14974 is a potent inhibitor of acid ceramidase with IC50 of 79 nM[1]. Target: Others. Smiles: Fc1ccc(cc1)-c1ccc2n(C(=O)NCCCCc3ccccc3)c(=O)oc2c1. References: Bach A, Pizzirani D, Realini N, Vozella V, Russo D, Penna I, Melzig L, Scarpelli R, Piomelli D....
Anwendung: Acid ceramidase inhibitor
CAS 1644158-57-5
MW: 404.43 D
ab 40,00 €
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ARN14988
ARN14988

Artikelnummer: TGM-T36468-10mg

Description: ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361...
Anwendung: Acid ceramidase inhibitor
CAS 1502027-70-4
MW: 373.83 D
ab 108,00 €
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C12-Ceramide
C12-Ceramide

Artikelnummer: TGM-T37436-10mg

Description: C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activity in the plasma of patients with Niemann-Pick disease. Smiles: CCCCCCCCCC...
Schlagworte: N-Laurylsphingosine, C12 Ceramide (d18:1/12:0), N-Lauroyl-D-erythro-sphingosine
Anwendung: Acid ceramidase substrate
CAS 74713-60-3
MW: 481.79 D
ab 145,00 €
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Anti-ASAH1
Anti-ASAH1

Artikelnummer: CSB-PA208943.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ASAH1. Antigen Species: Human
Schlagworte: Anti-ASAH, Anti-HSD-33, AC antibody, ACDase antibody, Acid CDase antibody, Acid ceramidase antibody, Acid ceramidase...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 167,00 €
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Anti-ASAH1
Anti-ASAH1

Artikelnummer: CSB-PA578122.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ASAH1. Antigen Species: Human
Schlagworte: Anti-ASAH, Anti-HSD-33, AC antibody, ACDase antibody, Acid CDase antibody, Acid ceramidase antibody, Acid ceramidase...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 167,00 €
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