BI-6C9

Description: BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death. Target: Mitochondrial Metabolism, Apoptosis. Smiles: COc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc1ccc(Sc2ccc(N)cc2)cc1. References: Grohm J , Plesnila N , Culmsee C . Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death[J]. Brain, Behavior, and Immunity, 2010, 24(5):0-838.