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BI-6C9
Artikelnummer: Cay17265-1
BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 µM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from...
| Schlagworte: | N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-butanamide |
| Anwendung: | tBid inhibitor |
| CAS | 791835-21-7 |
| MW: | 471.6 D |
ab 84,00 €
BI-6C9
Artikelnummer: TGM-T5827-100mg
Description: BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death. Target: Mitochondrial Metabolism, Apoptosis. Smiles: COc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc1ccc(Sc2ccc(N)cc2)cc1. References: Grohm J , Plesnila N , Culmsee C . Bid mediates...
| Anwendung: | tBid inhibitor |
| CAS | 791835-21-7 |
| MW: | 471.59 D |
ab 57,00 €
