Betahistine (hydrochloride)

Betahistine is a histamine H3 receptor antagonist and histamine H1 receptor agonist. In vivo, betahistine dilates pre-capillary arterioles and increases blood flow to the stria vascularis in guinea pigs. Betahistine (8 mg/kg) reduces weight gain and increased feeding behavior induced by olanzapine (Cay-11937) in female rats. Formulations containing betahistine have been used in the treatment of balance disorders and vertigo symptoms associated with Meniere's disease.Formal Name: N-methyl-2-pyridineethanamine, dihydrochloride. CAS Number: 5579-84-0. Molecular Formula: C8H12N2 . 2HCl. Formula Weight: 209.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2mg/mL, DMSO: 2mg/mL, Ethanol: 2.5mg/mL, PBS (pH 7.2): 5mg/mL. lambdamax: 261, 268 nm. SMILES: CNCCC1=CC=CC=N1.Cl.Cl. InChi Code: InChI=1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8,,/h2-4,6,9H,5,7H2,1H3,2*1H. InChi Key: XVDFMHARQUBJRE-UHFFFAOYSA-N.