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Zu "K04151" wurden 37 Artikel gefunden!
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Artikelnummer: ELK-ELK6556.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat HRH3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat HRH3. Next,...
Schlagworte: | H3R, HH3R, Hrh3, Histamine H3 receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: Cay10011127-1
Thioperamide (maleate) is a selective histamine H3 receptor antagonist that crosses the blood-brain barrier. This compound binds to rat cerebral cortical cells in vitro with a pKi value of 8.4 and inhibits histamine binding in vivo with an ED50 value of 1 mg/kg. At a dose of 5 mg/kg thioperamide (maleate) inhibits...
Schlagworte: | N-cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide, 2Z-butenedioate |
Anwendung: | Histamine H3 receptor antagonist |
CAS | 148440-81-7 |
MW: | 408.5 D |
ab 20,00 €
Artikelnummer: Cay10011126-1
Clobenpropit is a selective histamine H3 receptor antagonist (Ki = 0.17 nM in rat cortical membranes). Clobenpropit (0.3, 0.1, and 3 nM) reduces inhibition of electrically induced contractions in isolated guinea pig ileum longitudinal muscle by the H3 receptor agonist (R)-alpha-methylhistamine (Cay-25601). It does...
Schlagworte: | VUF 9153, N-[(4-chlorophenyl)methyl]-carbamimidothioic acid, 3-(1H-imidazol-5-yl)propyl ester, dihydrobromide |
Anwendung: | Histamine H3 receptor antagonist |
CAS | 145231-35-2 |
MW: | 470.7 D |
ab 50,00 €
Artikelnummer: Cay25601-1
R-(-)-alpha-Methylhistamine is a histamine H3 receptor agonist with diverse biological activities. It inhibits the release of histamine induced by antidromic electrical stimulation of the sciatic nerve in rats when administered at doses ranging from 0.25 to 2 mg/kg, an effect that can be reversed by the selective...
Schlagworte: | (alphaR)-methyl-1H-imidazole-5-ethanamine, dihydrochloride |
Anwendung: | Histamine H3 receptor agonist |
CAS | 75614-89-0 |
MW: | 198.1 D |
ab 43,00 €
Artikelnummer: Cay27602-1
Betahistine is a histamine H3 receptor antagonist and histamine H1 receptor agonist. In vivo, betahistine dilates pre-capillary arterioles and increases blood flow to the stria vascularis in guinea pigs. Betahistine (8 mg/kg) reduces weight gain and increased feeding behavior induced by olanzapine (Cay-11937) in...
Schlagworte: | N-methyl-2-pyridineethanamine, dihydrochloride |
Anwendung: | Histamine H3 receptor antagonist, Histamine H1 receptor agonist |
CAS | 5579-84-0 |
MW: | 209.1 D |
ab 43,00 €
Artikelnummer: Cay11700-100
Conessine is a steroidal alkaloid that has been found in H. antidysenterica and has diverse biological activities. It is active against a variety of Gram-positive and Gram-negative bacteria, including B. subtilis, S. aureus, M. luteus, and E. coli (MICs = 15.6-1,000 µg/disc in agar diffusion assays), the amoeba E....
Schlagworte: | Neriine, NSC 119994, Roquessine, Wrightine, N,N-dimethyl-con-5-enin-3beta-amine |
Anwendung: | Allergy/Asthma studies |
CAS | 546-06-5 |
MW: | 356.6 D |
ab 161,00 €
Artikelnummer: NSJ-R30304
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The histamine receptor H3(HRH3) is a presynaptic autoreceptor on histamine neurons in the brain and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. The deduced 445-amino acid HRH3 protein...
Schlagworte: | Anti-H3R, Anti-HRH3, Anti-HH3R, Anti-GPCR97, Anti-Histamine H3 receptor, Anti-G-protein coupled receptor 97, HRH3 Antibody |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: NSJ-R36104-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Histamine H3 receptor Protein function: The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of...
Schlagworte: | Anti-H3R, Anti-HRH3, Anti-HH3R, Anti-GPCR97, Anti-Histamine H3 receptor, Anti-G-protein coupled receptor 97, HRH3 Antibody |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: Cay19307-1
Pitolisant is a nonimidazole histamine H3 receptor antagonist (Ki = 0.16 nM) and inverse agonist (EC50 = 1.5 nM). It increases the levels of tele-methylhistamine in mouse brain, indicating histaminergic neuron activity, with an ED50 value of 1.6 mg/kg. Pitolisant also increases dopamine and acetylcholine levels in...
Schlagworte: | BF 2649, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine, monohydrochloride |
Anwendung: | Histamine H3 receptor antagonist / inverse agonist |
CAS | 903576-44-3 |
MW: | 332.3 D |
ab 50,00 €
Artikelnummer: E-AB-13309.120
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an...
Schlagworte: | Anti-H3R, Anti-HRH3, Anti-HH3R, Anti-GPCR97, Anti-Histamine H3 receptor, Anti-G-protein coupled receptor 97, HRH3... |
Anwendung: | WB, IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Artikelnummer: Cay11997-1
JNJ-10181457 is an antagonist of histamine H3 receptors (Kis = 1.17 and 7.08 nM for human and rat receptors, respectively). It increases extracellular norepinephrine and acetylcholine levels in the frontal cortex of rats when administered subcutaneously at a dose of 10 mg/kg. JNJ-10181457 (1.25-10 mg/kg, p.o.)...
Schlagworte: | RWJ 662733, 4-[[3-[4-(1-piperidinyl)-1-butyn-1-yl]phenyl]methyl]-morpholine, dihydrochloride |
Anwendung: | H3 Receptor antagonist |
CAS | 544707-20-2 |
MW: | 385.4 D |
ab 43,00 €
Artikelnummer: Cay11998-10
Histamine has been implicated in a variety of biological functions including thermo- and immunoregulation, food intake, hyperexcitability, pain transmission, arousal, reward, memory, and emotional responses. The histamine H3 receptor is a Gi-coupled presynaptic auto- and hetero-receptor whose activation leads to a...
Schlagworte: | 1-[3-[4-(1-piperidinylmethyl)phenoxy]propyl]-piperidine |
Anwendung: | Histamine H3R antagonist |
CAS | 398473-34-2 |
MW: | 316.5 D |
ab 119,00 €