BAY-885

BAY-885 is an inhibitor of ERK5 (IC50 = 0.035 µM). It inhibits ERK5-induced transcription in SN12C-MEF2 reporter cells (IC50 = 0.12 µM).Formal Name: [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-methanone. CAS Number: 2307249-33-6. Molecular Formula: C25H28F3N7O2. Formula Weight: 515.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: Soluble. lambdamax: 257 nm. SMILES: O=C(N1CCC(CC1)C2=NC=NC3=C2N=CC(N4CCN(CC4)C)=C3)C5=CC=C(C=C5N)OC(F)(F)F. InChi Code: InChI=1S/C25H28F3N7O2/c1-33-8-10-34(11-9-33)17-12-21-23(30-14-17)22(32-15-31-21)16-4-6-35(7-5-16)24(36)19-3-2-18(13-20(19)29)37-25(26,27)28/h2-3,12-16H,4-11,29H2,1H3. InChi Key: QXURFIGBRGWPQD-UHFFFAOYSA-N.