Zu "K04464" wurden 27 Artikel gefunden!
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Anti-ERK5 / MAPK7
Artikelnummer: NSJ-RQ7093
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical...
| Schlagworte: | Anti-BMK1, Anti-ERK-5, Anti-MAPK7, Anti-BMK-1, Anti-MAPK 7, Anti-MAP kinase 7, EC=2.7.11.24, Anti-Big MAP kinase 1,... |
| Anwendung: | WB, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
755,00 €
Anti-ERK5
Artikelnummer: ELK-EA166.100
ERK5, Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene. MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as...
| Schlagworte: | Anti-BMK1, Anti-MAPK7, Anti-BMK-1, Anti-ERK-5, Anti-MAPK 7, Anti-MAP kinase 7, EC=2.7.11.24, Anti-Big MAP kinase 1,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
XMD8-92
Artikelnummer: Cay19173-10
XMD8-92 is an ERK5 inhibitor (Kd = 80 nM) that less potently inhibits DCAMKL2, TNK1, and Plk4 (Kds = 190, 890, and 600 nM, respectively) in a panel of 402 kinases. It blocks ERK5 autophosphorylation, ERK5-mediated phosphorylation of promyelocytic leukemia protein (PML), and PML-dependent activation of p21. XMD8-92...
| Schlagworte: | 2-[[2-ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Anwendung: | ERK5 inhibitor |
| CAS | 1234480-50-2 |
| MW: | 474.6 D |
ab 43,00 €
XMD17-109
Artikelnummer: Cay25448-5
XMD17-109 is a selective ERK5 inhibitor (IC50 = 0.162 µM in an enzyme assay). It is selective for ERK5 over a panel of more than 200 kinases, inhibiting only ERK5 with greater than 90% target occupancy at a concentration of 10 µM. XMD17-109 inhibits ERK5 phosphorylation (IC50 = 0.09 µM in HeLa cells) and decreases...
| Schlagworte: | ERK5-IN-1,... |
| Anwendung: | Selective ERK5 inhibitor |
| CAS | 1435488-37-1 |
| MW: | 638.8 D |
ab 44,00 €
XMD8-85
Artikelnummer: Cay29662-5
XMD8-85 is an ERK5 inhibitor (IC50 = 87 nM in an enzyme assay). It is selective for ERK5 over tyrosine non-receptor kinase 2 (TNK2, IC50 = 959 nM), but does inhibit the leucine-rich repeat kinase 2 (LRRK2) mutant LRRK2G2019S (IC50 = 26 nM), which has been found in patients with Parkinson's disease. XMD8-85 inhibits...
| Schlagworte: | ERK5-IN-1,... |
| Anwendung: | ERK5 inhibitor |
| CAS | 1234479-76-5 |
| MW: | 459.5 D |
ab 60,00 €
Anti-ERK5
Artikelnummer: A302-655A
Protein function: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through...
| Schlagworte: | Anti-BMK1, Anti-MAPK7, Anti-ERK-5, Anti-BMK-1, Anti-MAPK 7, EC=2.7.11.24, Anti-MAP kinase 7, Anti-Big MAP kinase 1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-ERK5
Artikelnummer: A302-656A
Protein function: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through...
| Schlagworte: | Anti-BMK1, Anti-MAPK7, Anti-ERK-5, Anti-BMK-1, Anti-MAPK 7, EC=2.7.11.24, Anti-MAP kinase 7, Anti-Big MAP kinase 1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-MAP Kinase 7(erk5), clone 12F2
Artikelnummer: 0223-100
| Schlagworte: | Anti-Erk5, Anti-MAPK7 |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, dog |
383,00 €
Anti-ERK5
Artikelnummer: NSJ-F50463-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues,...
| Schlagworte: | Anti-BMK1, Anti-ERK-5, Anti-MAPK7, Anti-BMK-1, Anti-MAPK 7, EC=2.7.11.24, Anti-MAP kinase 7, Anti-Big MAP kinase 1,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-MAPK7
Artikelnummer: E-AB-14064.120
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically...
| Schlagworte: | Anti-BMK1, Anti-BMK-1, Anti-ERK-5, Anti-MAPK7, Anti-MAPK 7, EC=2.7.11.24, Anti-MAP kinase 7, Anti-Big MAP kinase 1,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-ERK 5
Artikelnummer: E-AB-60614.120
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically...
| Schlagworte: | Anti-BMK1, Anti-MAPK7, Anti-ERK-5, Anti-BMK-1, Anti-MAPK 7, Anti-MAP kinase 7, EC=2.7.11.24, Anti-Big MAP kinase 1,... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 198,00 €
Anti-MAPK7 / ERK5
Artikelnummer: ARG41798.100
Protein function: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through...
| Schlagworte: | Anti-BMK1, Anti-MAPK7, Anti-ERK-5, Anti-BMK-1, Anti-MAPK 7, Anti-MAP kinase 7, EC=2.7.11.24, Anti-Big MAP kinase 1,... |
| Anwendung: | FC, ICC, IF, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €