Azelnidipine

Azelnidipine is a third generation, dihydropyridine L-type calcium channel blocker with a slow onset profile that displays long-lasting antihypertensive activity in hypertensive rat models compared to other L-type calcium channel blockers.Formal Name: 2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester. CAS Number: 123524-52-7. Synonyms: CS 905, RS 9054. Molecular Formula: C33H34N4O6. Formula Weight: 582.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml, Ethanol: 15 mg/ml. lambdamax: 255, 343 nm. SMILES: CC1=C(C(OC(C)C)=O)C(C2=CC([N+]([O-])=O)=CC=C2)C(C(OC3CN(C(C4=CC=CC=C4)C5=CC=CC=C5)C3)=O)=C(N)N1. InChi Code: InChI=1S/C33H34N4O6/c1-20(2)42-32(38)27-21(3)35-31(34)29(28(27)24-15-10-16-25(17-24)37(40)41)33(39)43-26-18-36(19-26)30(22-11-6-4-7-12-22)23-13-8-5-9-14-23/h4-17,20,26,28,30,35H,18-19,34H2,1-3H3. InChi Key: ZKFQEACEUNWPMT-UHFFFAOYSA-N.