Zu "K04851" wurden 67 Artikel gefunden!
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Nimodipine
Artikelnummer: Cay14573-100
Nimodipine is an inhibitor of L-type voltage-gated calcium (CaV) channels. It is selective for CaV1.2 over CaV1.3 channels (IC50s = 0.139 and 2.7 µM, respectively), as well as R-, N-, and P/Q-type Cav channels at 10 µM. Nimodipine (0.72-24 nM) inhibits contractions induced by potassium, but not norepinephrine, in...
| Schlagworte: | BAY-e 9736, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(2-methoxyethyl) 5-(1-methylethyl)... |
| Anwendung: | Ca2+ channel antagonist |
| CAS | 66085-59-4 |
| MW: | 418.4 D |
ab 54,00 €
Nifedipine
Artikelnummer: Cay11106-10
Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 µM. Nifedipine (1 µM) reduces TGF-beta-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse...
| Schlagworte: | BAY 1040, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3,5-dimethyl ester |
| Anwendung: | Dihydropyridine calcium channel blocker |
| CAS | 21829-25-4 |
| MW: | 346.3 D |
ab 30,00 €
(±)-Verapamil-d3 (hydrochloride)
Artikelnummer: Cay18452-5
(±)-Verapamil-d3 (hydrochloride) (Cay-18452) is intended for use as an internal standard for the quantification of verapamil (Cay-14288) by GC- or LC-MS. Verapamil is the prototypical blocker of L-type calcium channels that produces excitation-contraction uncoupling in cardiac muscle by preventing the slow-inward...
| Schlagworte: | 5-((3,4-dimethoxyphenethyl)(methyl-d3)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile, monohydrochloride |
| Anwendung: | MS, internal control, calcium channel L type blocker, KCNJ6, KCNA10, KCNA3, KCNA7, KCNC2 blocker |
| CAS | 2714485-49-9 |
| MW: | 494.1 D |
ab 73,00 €
(S)-(-)-BAY-K-8644
Artikelnummer: Cay19988-5
(S)-(-)-BAY-K-8644 is an activator of voltage-sensitive L-type calcium channels. It demonstrates vasoconstrictive and positive inotropic effects in vivo as well as behavioral effects, including deficits to motor function. When combined with BIX01294 (Cay-13124), (S)-(-)-BAY-K-8644 can enable reprogramming of mouse...
| Schlagworte: | (4S)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester |
| Anwendung: | Voltage-sensitive L-type calcium channel activator |
| CAS | 98625-26-4 |
| MW: | 356.3 D |
ab 49,00 €
Barnidipine (hydrochloride)
Artikelnummer: Cay20448-10
Barnidipine is a dihydropyridine calcium channel blocker that has an IC50 value of 0.35 nM in potassium-induced tonic contraction of pig coronary artery. It demonstrates antihypertensive activity by reducing peripheral vascular resistance. It decreases blood pressure in spontaneously hypertensive rats when...
| Schlagworte: | YM-09730-5, (4S)-3,5-pyridinedicarboxylic acid, 3-methyl 5-[(3S)-1-(phenylmethyl)-3-pyrrolidinyl] ester, monohydrochloride |
| Anwendung: | Calcium channel blocker |
| CAS | 104757-53-1 |
| MW: | 528 D |
ab 38,00 €
Anti-CaV1.3, clone S48A-9
Artikelnummer: ARG22278.50
Protein function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The...
| Schlagworte: | Anti-RBD, Anti-Cach3, Anti-Cacna1d, Anti-Rat brain class D, Anti-Voltage-gated calcium channel subunit alpha Cav1.3,... |
| Anwendung: | WB, IHC, ICC, IF, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
584,00 €
Nilvadipine
Artikelnummer: Cay21243-10
Nilvadipine is a dihydropyridine L-type calcium channel blocker. It is selective for L-type over N-, P/Q-, and R-type calcium channels at 10 µM. Nilvadipine (10 mg/kg per day, p.o.) inhibits increases in systolic blood pressure induced by chronic intravenous infusion of the peptide vasoconstrictor endothelin in...
| Schlagworte: | (±)-Nilvadipine, CL 287,389, FK-235, FR34235, SKF 102362,... |
| Anwendung: | Calcium channel L-type blocker |
| CAS | 75530-68-6 |
| MW: | 385.4 D |
ab 49,00 €
Anti-Cav1.3, clone S48A-9
Artikelnummer: 200-301-F09
Anti-Cav1.3 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Cav1.3 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against Cav1.2. Cross-reactivity with Cav1.3 from other sources has not been determined....
| Schlagworte: | Anti-RBD, Anti-Cach3, Anti-Cacna1d, Anti-Rat brain class D, Anti-Voltage-gated calcium channel subunit alpha Cav1.3,... |
| Anwendung: | IHC, IFM, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
752,00 €
Anti-CACNA1D CaV1.3
Artikelnummer: NSJ-R31417
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cav1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent...
| Schlagworte: | Anti-CACH3, Anti-CACNA1D, Anti-Voltage-gated calcium channel subunit alpha Cav1.3, Anti-Calcium channel, L type, alpha-1... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-CaV1.3
Artikelnummer: NSJ-R31742
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CACNA1D is also known as PASNA, SANDD or Cav1.3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or...
| Schlagworte: | Anti-CACH3, Anti-CACNA1D, Anti-Voltage-gated calcium channel subunit alpha Cav1.3, Anti-Calcium channel, L type, alpha-1... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-CACNA1D
Artikelnummer: E-AB-16291.120
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta,...
| Schlagworte: | Anti-CACH3, Anti-CACNA1D, Anti-Voltage-gated calcium channel subunit alpha Cav1.3, Anti-Calcium channel, L type, alpha-1... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 89,00 €
(R)-(+)-BAY-K-8644
Artikelnummer: Cay15263-10
BAY-K-8644, originally described as a modulator of potential operated calcium channels, exists as two enantiomers that have opposite actions. (R)-(+)-BAY-K-8644 is an L-type channel blocker that has negative inotropic and vasodilatory effects at 1 µM. Intracerebroventricular administration of this enantiomer has no...
| Schlagworte: | NI 105, R 4407, (4R)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid |
| Anwendung: | L-type channel blocker |
| CAS | 98791-67-4 |
| MW: | 356.3 D |
ab 163,00 €