ATIC-IN-2

An IMP cyclohydrolase inhibitor (Ki = 0.13 µM), selective for the IMP cyclohydrolase activity of ATIC over the AICAR transformylase activity of ATIC and over GAR transformylase (Kis = >100 µM for both), has been found in A. leucotrichus. SMILES: O=S(NC1=C(NC=N1)C2=O)(N2)=O. InChi Code: InChI=1S/C4H4N4O3S/c9-4-2-3(6-1-5-2)7-12(10,11)8-4/h1,7H,(H,5,6)(H,8,9). InChi Key: BSAXWMSAVVOOHO-UHFFFAOYSA-N