AMT (hydrochloride)

AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations, the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.Formal Name: 5,6-dihydro-6-methyl-4H-1,3-thiazin-2-amine, hydrochloride. CAS Number: 21463-31-0. Molecular Formula: C5H10N2S . HCl. Formula Weight: 166.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: >8 mg/ml, DMSO: >16 mg/ml, Ethanol: >25 mg/ml, Water: >25 mg/ml. SMILES: CC1CCN=C(N)S1. InChi Code: InChI=1S/C5H10N2S.ClH/c1-4-2-3-7-5(6)8-4,/h4H,2-3H2,1H3,(H2,6,7),1H. InChi Key: HVJCRMIQAMEJNM-UHFFFAOYSA-N.