AMAROGENTIN

Description: Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis. Target: AMPK, Apoptosis. Smiles: OCC1OC(OC2OC=C3C(CCOC3=O)C2C=C)C(OC(=O)c2c(O)cc(O)cc2-c2cccc(O)c2)C(O)C1O. References: Shantanu S , Khushboo B , Durai S , et al. The Bitter Barricading of Prostaglandin Biosynthesis Pathway: Understanding the Molecular Mechanism of Selective Cyclooxygenase-2 Inhibition by Amarogentin, a Secoiridoid Glycoside from Swertia chirayita[J]. PLoS ONE, 2014, 9(3):e90637-.