Adenosine Dialdehyde (ADOX)

Description: Adenosine Dialdehyde (Periodate-oxidized adenosine) is a purine nucleoside analogue. Adenosine Dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo. Target: Others. Smiles: C(OC(CO)C=O)(C=O)N1C=2C(N=C1)=C(N)N=CN2. References: G V Madhavan, et al. Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem.