Zu "K01251" wurden 93 Artikel gefunden!
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Anti-AHCY / Adenosylhomocysteinase
Artikelnummer: NSJ-FY13365
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. AHCY antibody detects Adenosylhomocysteinase, an essential cytoplasmic enzyme encoded by the AHCY gene located on chromosome 20q11.22. AHCY catalyzes the reversible hydrolysis of S-adenosylhomocysteine (SAH) to adenosine and homocysteine, a...
| Schlagworte: | Anti-AHCY, Anti-Adenosylhomocysteinase, Anti-S-adenosyl-L-homocysteine hydrolase, AHCY Antibody / Adenosylhomocysteinase |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
S-Adenosyl-Homocysteine Hydrolase (SAHH) Activity...
Artikelnummer: E-BC-K841-M.96
In mammalian cells, S-adenosine homocysteine hydrolase (SAHH) is the only hydrolase involved in the hydrolysis of S-adenosine homocysteine (SAH) to homocysteine (Hcy). Excessive SAHH activity can hydrolyze SAH to generate excessive Hcy, thereby causing geriatric diseases such as Alzheimer's disease,...
426,00 €
Adenosine Dialdehyde
Artikelnummer: Cay15644-10
Adenosine dialdehyde is an irreversible inhibitor of S-adenosylhomocysteine (SAH, Cay-13603, Cay-9000372) hydrolase (IC50 = 40 nM), blocking the conversion of SAH to homocysteine and adenosine (Cay-21232). This reduces the amount of homocysteine that can be converted to methionine and, subsequently,...
| Schlagworte: | 6-amino-alpha-(1-formyl-2-hydroxyethoxy)-9H-purine-9-acetaldehyde |
| Anwendung: | AdoHcyase inhibitor |
| CAS | 34240-05-6 |
| MW: | 265.2 D |
ab 48,00 €
(-)-Neplanocin A
Artikelnummer: Cay10584-500
S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine. The inhibition of SAH hydrolase causes the intracellular accumulation of SAH, elevating the ratio of SAH to S-adenosylmethionine (SAM) and inhibiting SAM-dependent methyltransferase. (-)-Neplanocin A...
| Schlagworte: | 5R-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol |
| Anwendung: | SAH hydrolase inactivator |
| CAS | 72877-50-0 |
| MW: | 263.3 D |
ab 401,00 €
3-Deazaadenosine (hydrochloride)
Artikelnummer: Cay30969-1
3-Deazaadenosine (3-DZA) is an inhibitor of S-adenosylhomocysteine hydrolase (Ki = 3.9 µM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-kappaB signaling. 3-DZA also has antiviral and antibacterial...
| Schlagworte: | 3-DZA, c3Ado, deaza-Ado, 1-beta-D-ribofuranosyl-1H-imidazo[4,5-c]pyridin-4-amine, monohydrochloride |
| Anwendung: | S-adenosylhomocysteine hydrolase inhibitor |
| CAS | 86583-19-9 |
| MW: | 302.7 D |
ab 75,00 €
D-Eritadenine
Artikelnummer: Cay21747-1
D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase (SAAH, IC50 = 7 nM). It inhibits growth of C. parvum parasites (MIC50 = 3 µM) without exhibiting cytotoxicity in HCT-8 cells (CC50 = >1 mM). Dietary administration of D-eritadenine (50 mg/kg) increases liver...
| Schlagworte: | 6-amino-alphaR,betaR-dihydroxy-9H-purine-9-butanoic acid |
| Anwendung: | Adenosylhomocysteinase inhibitor |
| CAS | 23918-98-1 |
| MW: | 253.2 D |
ab 69,00 €
Ilimaquinone
Artikelnummer: Cay15124-100
Ilimaquinone is a natural sesquiterpene quinone that has antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties. In mammalian cells, 25 µM ilimaquinone reversibly induces vesiculation of Golgi membranes, blocking the secretory pathway. It inhibits the conversion of S-adenosylhomocysteine (SAH) to...
| Schlagworte: | 3-[[(1R,2S,4aS,8aS)-decahydro-1,2,4a-trimethyl-5-methylene-1-naphthalenyl]methyl]-2-hydroxy-5-methoxy-2,5-cyclohexadiene-1... |
| Anwendung: | SAH hydrolase inhibitor |
| CAS | 71678-03-0 |
| MW: | 358.5 D |
519,00 €
3-Deazaadenosine
Artikelnummer: Cay9000785-1
S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine. The inhibition of SAH hydrolase causes the intracellular accumulation of SAH, elevating the ratio of SAH to S-adenosylmethionine (SAM) and inhibiting SAM-dependent methyltransferases. 3-Deazaadenosine...
| Schlagworte: | 3-DZA, c3Ado, deaza-Ado, 1-beta-D-ribofuranosyl-1H-imidazo[4,5-c]pyridin-4-amine |
| Anwendung: | SAH hydrolase inhibitor |
| CAS | 6736-58-9 |
| MW: | 266.3 D |
ab 75,00 €
Coniferyl Alcohol
Artikelnummer: Cay29470-100
Coniferyl alcohol is a monolignol that has been found in pine sap. It is a precursor in the biosynthesis of lignin and has been used in the synthesis of lignin and a variety of phytochemicals. Coniferyl alcohol is an inhibitor of S-adenosyl-homocysteine hydrolase (SAAH) in vitro (IC50 = 34 nM). It increases the...
| Schlagworte: | Coniferol, 4-(3-hydroxy-1-propen-1-yl)-2-methoxy-phenol |
| Anwendung: | Monolignol, lignin biosynthesis precursor, S-adenosyl-homocysteine hydrolase (SAAH) inhibitor |
| CAS | 458-35-5 |
| MW: | 180.2 D |
ab 111,00 €
Anti-AHCY / Adenosylhomocysteinase
Artikelnummer: ARG57333.100
Protein function: Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions, therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. [The UniProt Consortium]
| Schlagworte: | Anti-AHCY, Anti-SAHH, Anti-AdoHcyase, EC=3.3.1.1, Anti-Adenosylhomocysteinase, Anti-S-adenosyl-L-homocysteine hydrolase |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Anti-SAH3
Artikelnummer: A300-261A
Protein function: May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg(2+)-sensitivity. On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1,4,5-trisphosphate (PubMed:19220705). [The UniProt Consortium]
| Schlagworte: | Anti-IRBIT2, Anti-AHCYL2, Anti-KIAA0828, EC=3.3.1.1, Anti-Long-IRBIT, Anti-AdoHcyase 3, Anti-Adenosylhomocysteinase 3,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
586,00 €
AHCY, GST-tag Recombinant
Artikelnummer: BPS-50260
Active human AHCY (human S-adenosyl homocysteine hydrolase) (GenBank Accession No. NM_000687), (amino acids 2-end) with N-terminal GST tag, MW = 73 kDa, expressed in an E Coli expression system.
| Schlagworte: | AHCY, SAHH, AdoHcyase, Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 73 kD |
812,00 €