Zu "K01251" wurden 82 Artikel gefunden!
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(-)-Neplanocin A
Artikelnummer: TGM-T84494-10mg
Description: S-Adenosylhomocysteine (SAH) hydrolase is responsible for the reversible hydrolysis of SAH into adenosine and homocysteine. Inhibition of this enzyme leads to the accumulation of SAH within cells, thereby increasing the SAH to S-adenosylmethionine (SAM) ratio and subsequently inhibiting SAM-dependent...
| Anwendung: | SAH hydrolase inactivator |
| CAS | 72877-50-0 |
| MW: | 263.3 D |
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CONIFERYL ALCOHOL
Artikelnummer: TGM-TL0010-100mg
Description: Coniferyl alcohol (Coniferol) is a fungal growth inhibitor. Target: Antifungal, Endogenous Metabolite. Smiles: COC1=C(O)C=CC(\C=C\CO)=C1. References: König S, et al. Soluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum[J]. New Phytologist, 2014,...
| Schlagworte: | Coniferol |
| Anwendung: | Monolignol, lignin biosynthesis precursor, S-adenosyl-homocysteine hydrolase (SAAH) inhibitor |
| CAS | 458-35-5 |
| MW: | 180.2 D |
ab 31,00 €
AHCY Protein, Human, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-00893-100ug
Description: Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions, therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. AHCY Protein, Human,...
| Schlagworte: | Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, SAHH, AdoHcyase |
| MW: | 63.6 kD |
ab 198,00 €
Eritadenine
Artikelnummer: TGM-T25385-10mg
Description: Eritadenine is a potent S-adenosyl-L-homocysteine hydrolase (SAHH) inhibitor, decreasing total cholesterol levels in plasma. Target: Others. Smiles: C([C@H]([C@H](C(O)=O)O)O)N1C=2C(N=C1)=C(N)N=CN2. References: Afrin S, Rakib MA, Kim BH, Kim JO, Ha YL. Eritadenine from Edible Mushrooms Inhibits Activity...
| Schlagworte: | Lentinacin, Lentysine, D-Eritadenine |
| Anwendung: | Adenosylhomocysteinase inhibitor |
| CAS | 23918-98-1 |
| MW: | 253.21 D |
ab 114,00 €
Adenosylhomocysteinase (AHCY), human, recombinant
Artikelnummer: CSB-EP001474HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-432aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: SDKLPYKVAD IGLAAWGRKA LDIAENEMPG LMRMRERYSA SKPLKGARIA GCLHMTVETA VLIETLVTLG AEVQWSSCNI FSTQDHAAAA IAKAGIPVYA WKGETDEEYL...
| Schlagworte: | SAHH, AHCY, AdoHcyase, EC=3.3.1.1, Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, Recombinant Human... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 63.6 kD |
ab 219,00 €
Adenosylhomocysteinase (SAH1), partial, Saccharomyces...
Artikelnummer: CSB-EP001474SVG1.1
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). Source: E.coli. Expression Region: 1-448aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSAPAQNYKI ADISLAAFGR KEIELAEHEM PGLMAIRKAY GDVQPLKGAR IAGCLHMTIQ TAVLIETLVA LGAEVTWSSC NIYSTQDHAA...
| Schlagworte: | SAH1, YER043C, AdoHcyase, EC=3.3.1.1, Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Saccharomyces cerevisiae |
| MW: | 53 kD |
ab 364,00 €
Adenosine Dialdehyde
Artikelnummer: Cay15644-10
Adenosine dialdehyde is an irreversible inhibitor of S-adenosylhomocysteine (SAH, Cay-13603, Cay-9000372) hydrolase (IC50 = 40 nM), blocking the conversion of SAH to homocysteine and adenosine (Cay-21232). This reduces the amount of homocysteine that can be converted to methionine and, subsequently,...
| Schlagworte: | 6-amino-alpha-(1-formyl-2-hydroxyethoxy)-9H-purine-9-acetaldehyde |
| Anwendung: | AdoHcyase inhibitor |
| CAS | 34240-05-6 |
| MW: | 265.2 D |
ab 43,00 €
(-)-Neplanocin A
Artikelnummer: Cay10584-500
S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine. The inhibition of SAH hydrolase causes the intracellular accumulation of SAH, elevating the ratio of SAH to S-adenosylmethionine (SAM) and inhibiting SAM-dependent methyltransferase. (-)-Neplanocin A...
| Schlagworte: | 5R-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol |
| Anwendung: | SAH hydrolase inactivator |
| CAS | 72877-50-0 |
| MW: | 263.3 D |
ab 369,00 €
3-Deazaadenosine (hydrochloride)
Artikelnummer: Cay30969-1
3-Deazaadenosine (3-DZA) is an inhibitor of S-adenosylhomocysteine hydrolase (Ki = 3.9 µM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-kappaB signaling. 3-DZA also has antiviral and antibacterial...
| Schlagworte: | 3-DZA, c3Ado, deaza-Ado, 1-beta-D-ribofuranosyl-1H-imidazo[4,5-c]pyridin-4-amine, monohydrochloride |
| Anwendung: | S-adenosylhomocysteine hydrolase inhibitor |
| CAS | 86583-19-9 |
| MW: | 302.7 D |
ab 69,00 €
D-Eritadenine
Artikelnummer: Cay21747-1
D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase (SAAH, IC50 = 7 nM). It inhibits growth of C. parvum parasites (MIC50 = 3 µM) without exhibiting cytotoxicity in HCT-8 cells (CC50 = >1 mM). Dietary administration of D-eritadenine (50 mg/kg) increases liver...
| Schlagworte: | 6-amino-alphaR,betaR-dihydroxy-9H-purine-9-butanoic acid |
| Anwendung: | Adenosylhomocysteinase inhibitor |
| CAS | 23918-98-1 |
| MW: | 253.2 D |
ab 63,00 €
Ilimaquinone
Artikelnummer: Cay15124-100
Ilimaquinone is a natural sesquiterpene quinone that has antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties. In mammalian cells, 25 µM ilimaquinone reversibly induces vesiculation of Golgi membranes, blocking the secretory pathway. It inhibits the conversion of S-adenosylhomocysteine (SAH) to...
| Schlagworte: | 3-[[(1R,2S,4aS,8aS)-decahydro-1,2,4a-trimethyl-5-methylene-1-naphthalenyl]methyl]-2-hydroxy-5-methoxy-2,5-cyclohexadiene-1... |
| Anwendung: | SAH hydrolase inhibitor |
| CAS | 71678-03-0 |
| MW: | 358.5 D |
286,00 €
3-Deazaadenosine
Artikelnummer: Cay9000785-1
S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine. The inhibition of SAH hydrolase causes the intracellular accumulation of SAH, elevating the ratio of SAH to S-adenosylmethionine (SAM) and inhibiting SAM-dependent methyltransferases. 3-Deazaadenosine...
| Schlagworte: | 3-DZA, c3Ado, deaza-Ado, 1-beta-D-ribofuranosyl-1H-imidazo[4,5-c]pyridin-4-amine |
| Anwendung: | SAH hydrolase inhibitor |
| CAS | 6736-58-9 |
| MW: | 266.3 D |
ab 69,00 €