ACY-957 (hydrochloride)

Artikelnummer	Größe	Manual	Lieferzeit	Preis
Cay43477-5	5 mg	-	6 - 10 Werktage*	186,00 €
Cay43477-10	10 mg	-	6 - 10 Werktage*	353,00 €
Cay43477-25	25 mg	-	6 - 10 Werktage*	836,00 €

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ACY-957 is an inhibitor of histone deacetylase 1 (HDAC1) and HDAC2 (IC50s = 7 and 18 nM,... mehr

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Produktinformationen "ACY-957 (hydrochloride)"

ACY-957 is an inhibitor of histone deacetylase 1 (HDAC1) and HDAC2 (IC50s = 7 and 18 nM, respectively). It is selective for HDAC1 and HDAC2 over HDAC3 (IC50 = 1,300 nM) and does not inhibit HDAC4-9 at concentrations up to 20 µM. ACY-957 (1 µM) induces expression of HBG, the gene encoding gamma-globin, in peripheral blood mononuclear cells (PBMCs) isolated from patients with sickle cell disease. SMILES NC1=C(NC(C2=CC(C=C3)=C(C=C2)N=C3N4CCNCC4)=O)C=C(C5=CC=CS5)C=C1.Cl InChi Code InChI=1S/C24H23N5OS.ClH/c25-19-6-3-17(22-2-1-13-31-22)15-21(19)28-24(30)18-4-7-20-16(14-18)5-8-23(27-20)29-11-9-26-10-12-29,/h1-8,13-15,26H,9-12,25H2,(H,28,30),1H InChi Key AACRPMFRIVUUMC-UHFFFAOYSA-N

Schlagworte:	N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-6-quinolinecarboxamide, monohydrochloride
Hersteller:	Cayman Chemical
Hersteller-Nr:	43477

Eigenschaften

Anwendung:	HDAC1 / HDAC2 inhibitor
MW:	466 D
Formel:	C24H23N5OS . HCl
Reinheit:	>98%
Format:	Solid

Datenbank Information

KEGG ID :

K06067 | Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H302, H315, H319, H335
P-Sätze:	P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501