Aconine

Description: 1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props. Target: NF-kappaB, Others. Smiles: CCN1C[C@@]2(COC)[C@H]3[C@@H](OC)C4C1C3([C@@H]1C[C@@]3(O)[C@H](O)[C@@H]1[C@]4(O)[C@@H](O)[C@@H]3OC)[C@H](C[C@H]2O)OC. References: Zeng X Z , He L G , Wang S , et al. Aconine inhibits RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing NF-kappaB and NFATc1 activation and DC-STAMP expression[J]. Acta Pharmacologica Sinica, 2015.