Abeprazan

A potassium-competitive acid blocker, increases TEER and occludin and Muc-1 levels at 20 µg/ml in a Caco-2 cell model of DSS-induced UC, reduces ileal levels of TNF-alpha, IL-6, and IL-1beta in a mouse model of IDM-induced small intestinal injury at 20 mg/kg. SMILES: O=S(C1=CC(F)=CC=C1)(N2C=C(CNC)C(OC)=C2C3=C(F)C=C(F)C=C3)=O. InChi Code: InChI=1S/C19H17F3N2O3S/c1-23-10-12-11-24(28(25,26)15-5-3-4-13(20)8-15)18(19(12)27-2)16-7-6-14(21)9-17(16)22/h3-9,11,23H,10H2,1-2H3. InChi Key: OUNXGNDVWVPCOL-UHFFFAOYSA-N