Zu "K01542" wurden 35 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Rabeprazole Sulfide
Artikelnummer: TGM-T1734-1mL
Description: Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors. Target: Antibacterial, Proton pump. Smiles: S(CC1=C(C)C(OCCCOC)=CC=N1)C=2NC=3C(N2)=CC=CC3. References: Ohara T, et al. Helicobacter. 2001 Jun,6(2):125-9.
| Schlagworte: | Rabeprazole Related Compound E |
| Anwendung: | Active Rabeprazole metabolite |
| CAS | 117977-21-6 |
| MW: | 343.44 D |
31,00 €
(R)-Omeprazole (sodium salt)
Artikelnummer: TGM-T36840-1mg
Description: (R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a...
| Anwendung: | H+/K+ exchanging, alpha / beta polypeptide inhibitor |
| CAS | 161796-77-6 |
| MW: | 368.41 D |
ab 198,00 €
K-transporting ATPase alpha chain 1 Inhibitor 1
Artikelnummer: TGM-T9553-100mg
Description: 8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car is a H+/K+ ATPase inhibitor with IC50 of 0.38µM. Target: Others. Smiles: N(CC1=C(C)C=CC=C1C)C=2C=3N(C=C(C(O)=O)C2)C(C)=C(C)N3
| Anwendung: | K-transporting ATPase alpha chain 1 inhibitor |
| CAS | 816450-73-4 |
| MW: | 323.39 D |
ab 88,00 €
ATP4A Protein, Human, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-01892-100ug
Description: ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.6 kDa and the accession number is P20648.
| Schlagworte: | Gastric H(+)/K(+) ATPase subunit alpha, Proton pump, Potassium-transporting ATPase alpha chain 1, ATP4A |
| MW: | 54.6 kD |
ab 281,00 €
Potassium-transporting ATPase alpha chain 1 (ATP4A),...
Artikelnummer: CSB-EP002342HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 350-783aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: TVTVCLSLTA KRLASKNCVV KNLEAVETLG STSVICSDKT GTLTQNRMTV SHLWFDNHIH TADTTEDQSG QTFDQSSETW RALCRVLTLC NRAAFKSGQD AVPVPKRIVI...
| Schlagworte: | ATP4A, EC=7.2.2.19, Proton pump, Gastric H(+)/K(+) ATPase subunit alpha, Potassium-transporting ATPase alpha chain 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 54.6 kD |
ab 292,00 €
Omeprazole
Artikelnummer: Cay14880-100
Omeprazole is an inhibitor of gastric H+/K+ ATPase (IC50 = 1.1 µM for the pig ATPase). It is a racemic mixture of esomeprazole (Cay-17303) and (R)-omeprazole (Cay-18874). Omeprazole (100 µM) decreases zymosan-induced oxygen free radical production in isolated human neutrophils. It is active against 17 strains of H....
| Schlagworte: | OMEP, OMP, OMZ, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole |
| Anwendung: | Gastric H+/K+ ATPase pump inhibitor |
| CAS | 73590-58-6 |
| MW: | 345.4 D |
ab 44,00 €
Pantoprazole
Artikelnummer: Cay21345-1
Pantoprazole is a proton pump inhibitor that inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles with an IC50 value of 6.8 µM. It reduces basal gastric acid secretion in pylorus-ligated rats (ED50 = 1.3 mg/kg) and inhibits mepirizole-induced increases in gastric acid secretion in an anesthetized rat...
| Schlagworte: | BY 1023, SKF 96022, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole |
| Anwendung: | Gastric H+/K+ ATPase pump inhibitor |
| CAS | 102625-70-7 |
| MW: | 383.4 D |
ab 44,00 €
(R)-Omeprazole (sodium salt)
Artikelnummer: Cay18874-1
(R)-Omeprazole is an inhibitor of the gastric H+/K+ ATPase and an enantiomer of esomeprazole (Cay-17303). It inhibits acid secretion induced by histamine (Cay-33828) in isolated rabbit gastric glands (IC50 = 781 µM) to a lesser extent than esomeprazole. (R)-Omeprazole (30 mg/kg) inhibits histamine-induced stomach...
| Schlagworte: | 6-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, monosodium salt |
| Anwendung: | H+/K+ exchanging, alpha / beta polypeptide inhibitor |
| CAS | 161796-77-6 |
| MW: | 368.4 D |
ab 111,00 €
Omeprazole-d3
Artikelnummer: Cay22087-1
Omeprazole-d3 is intended for use as an internal standard for the quantification of omeprazole (Cay-14880) by GC- or LC-MS. Omeprazole is an inhibitor of gastric H+/K+ ATPase (IC50 = 1.1 µM for the pig ATPase). It is a racemic mixture of esomeprazole (Cay-17303) and (R)-omeprazole (Cay-18874). Omeprazole (100 µM)...
| Schlagworte: | OMEP-d3, OMP-d3, OMZ-d3, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-4,5,7-d3 |
| Anwendung: | GC-MS, LC-MS, internal standard |
| CAS | 934293-92-2 |
| MW: | 348.4 D |
ab 159,00 €
Vonoprazan (fumarate)
Artikelnummer: Cay24200-500
Vonoprazan is a selective, reversible, and potassium-competitive proton pump inhibitor that inhibits gastric H+/K+ ATPase (IC50 = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration of 10 µM. It maintains its inhibitory effect in both weakly acidic (pH 6.5) and neutral (pH 7.5)...
| Schlagworte: | TAK-438, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine, 2-butenedioate |
| Anwendung: | Proton pump inhibitor |
| CAS | 1260141-27-2 |
| MW: | 461.5 D |
ab 61,00 €
Rabeprazole-d4 (sodium salt)
Artikelnummer: Cay26118-500
Rabeprazole-d4 is intended for use as an internal standard for the quantification of rabeprazole (Cay-14939) by GC- or LC-MS. Rabeprazole is a proton pump inhibitor that selectively and irreversibly inhibits the gastric H+/K+ ATPase (IC50 = 72 nM). It can be activated more rapidly and over a greater pH range than...
| Schlagworte: | 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole-4,5,6,7-d4, monosodium salt |
| Anwendung: | GC-MS, LC-MS, internal standard, proton pump inhibitor |
| MW: | 385.4 D |
ab 349,00 €
Rabeprazole
Artikelnummer: LKT-R0105.10
A proton pump/ATP-ase inhibitor.
| Schlagworte: | Rabeprazole Sodium, H+/K+ exchanging, alpha/beta polypeptide inhibitor |
| Anwendung: | Proton pump inhibitor |
| CAS | 117976-89-3 |
| MW: | 359,44 D |
ab 141,00 €