5-Aminofluorescein

5-Aminofluorescein is a fluorescent compound and an inhibitor of the mRNA N6-methyladenosine (m6A) demethylase fat mass and obesity-associated (FTO) protein (IC50 = 6.55 µM). It displays excitation/emission maxima of 490 and 515 nm, respectively, and has been conjugated to human serum albumin for fluorescence imaging of glioblastomas.Formal Name: 5-amino-3',6'-dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one. CAS Number: 3326-34-9. Synonyms: 5-AF, Fluoresceinamine isomer 1. Molecular Formula: C20H13NO5. Formula Weight: 347.3. Purity: >95%. Emission: 515 nm. Excitation: 490 nm. Formulation: (Request formulation change), A solid. Solubility: DMF: 5 mg/ml, DMSO: 5 mg/ml. lambdamax: 226 nm. SMILES: O=C1OC2(C3=CC=C(C=C13)N)C4=CC=C(C=C4OC5=CC(O)=CC=C52)O. InChi Code: InChI=1S/C20H13NO5/c21-10-1-4-14-13(7-10)19(24)26-20(14)15-5-2-11(22)8-17(15)25-18-9-12(23)3-6-16(18)20/h1-9,22-23H,21H2. InChi Key: GZAJOEGTZDUSKS-UHFFFAOYSA-N.