4'-hydroxyphenyl Carvedilol

4'-hydroxyphenyl Carvedilol is a metabolite of carvedilol (Cay-15418) that is a more potent beta-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4'-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.Formal Name: 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxy-phenol. CAS Number: 142227-49-4. Synonyms: BM 140686. Molecular Formula: C24H26N2O5. Formula Weight: 422.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: slightly soluble, Methanol: slightly soluble. SMILES: COC1=C(OCCNCC(COC2=C(C(C=CC=C3)=C3N4)C4=CC=C2)O)C=CC(O)=C1. InChi Code: InChI=1S/C24H26N2O5/c1-29-23-13-16(27)9-10-21(23)30-12-11-25-14-17(28)15-31-22-8-4-7-20-24(22)18-5-2-3-6-19(18)26-20/h2-10,13,17,25-28H,11-12,14-15H2,1H3. InChi Key: ZCJHEORDHXCJNB-UHFFFAOYSA-N.