2-Oleoyl Glycerol

2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG, Cay-62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases. 2-OG is an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.Formal Name: 2-hydroxy-1-(hydroxymethyl)ethyl ester-9Z-octadecenoic acid. CAS Number: 3443-84-3. Synonyms: 2-Monoolein, 2-OG. Molecular Formula: C21H40O4. Formula Weight: 356.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 15 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.25 mg/ml. SMILES: CCCCCCCC/C=C\CCCCCCCC(OC(CO)CO)=O. InChi Code: InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-. InChi Key: UPWGQKDVAURUGE-KTKRTIGZSA-N. Side Chain Carbon Sum: 18:1.