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Zu "K08424" wurden 17 Artikel gefunden!
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Artikelnummer: Cay16537-5
2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG, Cay-62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases. 2-OG is an agonist of GPR119...
Schlagworte: | 2-Monoolein, 2-OG, 2-hydroxy-1-(hydroxymethyl)ethyl ester-9Z-octadecenoic acid |
Anwendung: | GPR119 agonist |
CAS | 3443-84-3 |
MW: | 356.5 D |
ab 43,00 €
Artikelnummer: Cay22206-5
MBX-2982 is an agonist of GPR119. It reduces nuclear and total protein levels of sterol regulatory element binding protein 1 (SREBP-1) in HepG2 cells and rat primary hepatocytes under high-glucose and -insulin conditions and increases phosphorylation of the inhibitory form, SREBP-1c. MBX-2982 (10 mg/kg) inhibits...
Schlagworte: | 5-ethyl-2-[4-[4-[[4-(1H-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-pyrimidine |
Anwendung: | GPR119 agonist |
CAS | 1037792-44-1 |
MW: | 448.5 D |
ab 205,00 €
Artikelnummer: Cay10008594-1
GPR119 (previously designated SNORF25) is an orphan G protein-coupled receptor expressed predominantly in the pancreas and gastrointestinal tract in humans and in the brain, pancreas, and gastrointestinal tract in rodents. It mediates a reduction in food intake and body weight gain in rats upon treatment with oleoyl...
Schlagworte: | 4-[[3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]methoxy]-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester |
Anwendung: | GPR119 receptor agonist |
CAS | 857652-30-3 |
MW: | 360.4 D |
ab 38,00 €
Artikelnummer: Cay13637-10
Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
Schlagworte: | N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide |
Anwendung: | GPR119 agonist |
CAS | 72809-08-6 |
MW: | 355.6 D |
ab 56,00 €
Artikelnummer: Cay17642-5
GPR119, a glucose-dependent insulinotropic receptor, is a G protein-coupled receptor that is expressed in pancreatic beta-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine (Cay-10172) and oleoyl ethanolamide (Cay-90265) increases intracellular cAMP levels and...
Schlagworte: | JNJ-28630368, 4-[[1-[2-fluoro-4-(methylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy]-1-piperidinecarboxylic acid,... |
Anwendung: | GPR119 agonist |
CAS | 832714-46-2 |
MW: | 477.5 D |
ab 60,00 €
Artikelnummer: Cay26181-5
GSK1292263 is an agonist of G protein-coupled receptor 119 (GPR119, EC50 = 43.9 nM in CHO-K1 cells expressing human receptors). It inhibits increases in sterol regulatory element binding protein-1 (SREBP-1) levels induced by the LXR agonist T0901317 and increases activation of AMPK in HepG2 cells in a...
Schlagworte: | 5-[[1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl]methoxy]-2-[4-(methylsulfonyl)phenyl]-pyridine |
Anwendung: | GPR119 agonist |
CAS | 1032823-75-8 |
MW: | 456.6 D |
ab 160,00 €
Artikelnummer: ARG64613.100
Protein function: Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated...
Schlagworte: | Anti-GPR119, Anti-G-protein coupled receptor 119, Anti-Glucose-dependent insulinotropic receptor |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
784,00 €
Artikelnummer: NSJ-R35841-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: G protein-coupled receptor 119 Protein function: Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent...
Schlagworte: | Anti-GPR119, Anti-G-protein coupled receptor 119, Anti-Glucose-dependent insulinotropic receptor, GPR119 Antibody |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: Cay10626-1
GPR119, a glucose-dependent insulinotropic receptor, is a Gs protein-coupled receptor that is expressed in pancreas beta-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine and oleoyl ethanolamide increases intracellular cAMP levels and promotes glucose-stimulated...
Schlagworte: | 2-[[2-(4-bromophenyl)-6-methyl-4-pyrimidinyl]amino]-ethanol |
Anwendung: | GPR119 agonist |
CAS | 330981-72-1 |
MW: | 308.2 D |
ab 43,00 €
Artikelnummer: Cay22950-10
APD597 is an orally bioavailable agonist of GPR119 that has EC50 values of 46 and 421 nM for the human and rat receptors, respectively, in a homologous time-resolved fluorescence (HTRF) assay. It increases insulin secretion stimulated by a high, but not low, concentration of glucose in isolated mouse pancreatic...
Schlagworte: | JNJ-38431055, 4-[[5-methoxy-6-[[2-methyl-6-(methylsulfonyl)-3-pyridinyl]amino]-4-pyrimidinyl]oxy]-1-piperidinecarboxylic... |
Anwendung: | GPR119 agonist |
CAS | 897732-93-3 |
MW: | 479.6 D |
ab 125,00 €
Artikelnummer: Cay10008593-1
GPR119 (previously designated SNORF25) is an orphan G protein-coupled receptor expressed predominantly in the pancreas and gastrointestinal tract in humans and in the brain, pancreas, and gastrointestinal tract in rodents. It mediates a reduction in food intake and body weight gain in rats upon treatment with oleoyl...
Schlagworte: | 4-[5-(4-butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridine |
Anwendung: | GPR119 agonist |
CAS | 388575-52-8 |
MW: | 285.4 D |
ab 24,00 €
Artikelnummer: E-AB-19928.120
This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a...
Schlagworte: | Anti-GPR119, Anti-G-protein coupled receptor 119, Anti-Glucose-dependent insulinotropic receptor, GPR119 Polyclonal Antibody |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 71,00 €