11alpha-Hydroxyprogesterone

Description: 11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11beta-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an effective dose (ED)50 of 10 nM. Target: Others. Smiles: [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)C[C@@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C