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11alpha-Hydroxyprogesterone
11alpha-Hydroxyprogesterone

Artikelnummer: Cay35898-1

11alpha-Hydroxyprogesterone (11alpha-OHP) is an inhibitor of 11beta-hydroxysteroid dehydrogenase (IC50s = 0.63 and 0.4 µM for recombinant human 11beta-HSD1 and 11beta-HSD2, respectively) and a derivative of the endogenous hormone progesterone (Cay-15876). 11alpha-OHP (10, 100, and 500 µg/animal) reduces urinary...
Schlagworte: 11alpha-OHP, NSC 3350, U-0384, 11alpha-hydroxy-pregn-4-ene-3,20-dione
Anwendung: 11-HSD inhibitor, progesterone derivative
CAS 80-75-1
MW: 330.5 D
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11alpha-Hydroxyprogesterone
11alpha-Hydroxyprogesterone

Artikelnummer: TGM-T84842-10mg

Description: 11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11beta-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an...
Anwendung: 11-HSD inhibitor, progesterone derivative
CAS 80-75-1
MW: 330.468 D
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