10-Chloroestra-1,4-diene-3,17-dione

Description: 10-Chloroestra-1,4-diene-3,17-dione acts as an estrogen receptor alpha (ERalpha) agonist, enhancing reporter gene expression in S. cerevisiae with an EC50 of 0.36 nM for the human receptor. Additionally, it functions as an aromatase inhibitor, exhibiting an IC50 of 2.4 µM. Target: Others. Smiles: Cl[C@@]12[C@]3([H])[C@](CCC1=CC(C=C2)=O)([H])[C@@]4([H])[C@](CC3)(C(CC4)=O)C